Label Type Identifier Comment Ensembl NCBI gene HGNC UniProt Wikidata ChEBI InChI 5-fluorouracil (5-FU) Metabolite chebi:46345 wikidata:Q238512 chebi:46345;chebi:46345 inchikey:OGJRKILIPRVJFS-GOJJZGEOSA-N;inchikey:GHASVSINZRGABV-UHFFFAOYSA-N Capecitabine Metabolite chebi:31348 wikidata:Q420207 chebi:31348;chebi:31348 inchikey:GAGWJHPBXLXJQN-UORFTKCHSA-N 5-dFUR Metabolite wikidata:Q1253473 wikidata:Q1253473 chebi:31521;chebi:31521 inchikey:ZWAOHEXOSAUJHY-ZIYNGMLESA-N dTMP Metabolite hmdb:HMDB0001227 chebi:17013;chebi:17013 inchikey:GYOZYWVXFNDGLU-XLPZGREQSA-N FUTP Metabolite pubchem.compound:10255482 wikidata:Q42412399 inchikey:AREUQFTVCMGENT-UAKXSSHOSA-N FUPA Metabolite pubchem.compound:151244 wikidata:Q27149673 chebi:80625;chebi:80625 inchikey:FKTHAKABFGARQH-UHFFFAOYSA-N FdUTP Metabolite pubchem.compound:503023 wikidata:Q41596188 inchikey:YQOCUTDPKPPQGA-RRKCRQDMSA-N Tegafur Metabolite chemspider:5193 wikidata:Q413370 chebi:32188;chebi:32188 inchikey:WFWLQNSHRPWKFK-UHFFFAOYSA-N Leucovorin Metabolite pubchem.compound:135403648 wikidata:Q45435667 chebi:15640;chebi:15640 inchikey:VVIAGPKUTFNRDU-ABLWVSNPSA-N dUMP Metabolite hmdb:HMDB0001409 chebi:17622;chebi:17622 inchikey:JSRLJPSBLDHEIO-SHYZEUOFSA-N 5-FU Metabolite chebi:46345 wikidata:Q238512 chebi:46345;chebi:46345 inchikey:OGJRKILIPRVJFS-GOJJZGEOSA-N;inchikey:GHASVSINZRGABV-UHFFFAOYSA-N FUDP Metabolite pubchem.compound:46936877 wikidata:Q27094920 inchikey:WLQBZMZTRNPUDL-BBVRLYRLSA-N FUMP Metabolite cas:796-66-7 wikidata:Q27120389 chebi:40101;chebi:40101 inchikey:RNBMPPYRHNWTMA-UAKXSSHOSA-N 5-FU Metabolite chebi:46345 wikidata:Q238512 chebi:46345;chebi:46345 inchikey:OGJRKILIPRVJFS-GOJJZGEOSA-N;inchikey:GHASVSINZRGABV-UHFFFAOYSA-N FBAL Metabolite pubchem.compound:13351 wikidata:Q27149674 chebi:80626;chebi:80626 inchikey:OJQNRNQELNLWHH-UHFFFAOYSA-N FUTP Metabolite pubchem.compound:10255482 wikidata:Q42412399 inchikey:AREUQFTVCMGENT-UAKXSSHOSA-N 5,10-Methylenetetrahydrofolate Metabolite chemspider:97272 wikidata:Q192838 chebi:20502;chebi:20502 inchikey:QYNUQALWYRSVHF-ABLWVSNPSA-N FdUTP Metabolite pubchem.compound:503023 wikidata:Q41596188 inchikey:YQOCUTDPKPPQGA-RRKCRQDMSA-N FdUDP Metabolite pubchem.compound:53882537 wikidata:Q41596157 inchikey:HKUJAJKSNVIDLX-RRKCRQDMSA-N 5-FU Metabolite chebi:46345 wikidata:Q238512 chebi:46345;chebi:46345 inchikey:OGJRKILIPRVJFS-GOJJZGEOSA-N;inchikey:GHASVSINZRGABV-UHFFFAOYSA-N Dihydrofolate Metabolite hmdb:HMDB0001056 chebi:15633;chebi:15633 inchikey:OZRNSSUDZOLUSN-LBPRGKRZSA-N FUDR Metabolite wikidata:Q5462356 wikidata:Q5462356 chebi:60761;chebi:60761 inchikey:ODKNJVUHOIMIIZ-RRKCRQDMSA-N FdUMP Metabolite pubchem.compound:8642 wikidata:Q27105559 chebi:2129;chebi:2129 inchikey:HFEKDTCAMMOLQP-RRKCRQDMSA-N FdUMP Metabolite pubchem.compound:8642 wikidata:Q27105559 chebi:2129;chebi:2129 inchikey:HFEKDTCAMMOLQP-RRKCRQDMSA-N 5-dFCR Metabolite pubchem.compound:10037499 wikidata:Q27149675 chebi:80627;chebi:80627 inchikey:YSNABXSEHNLERR-ZIYNGMLESA-N;inchikey:ZEPNVCGPJXYABB-CPGDAPNVSA-N DHFU Metabolite pubchem.compound:121997 wikidata:Q27149672 chebi:80624;chebi:80624 inchikey:RAIRJKWTBBDDAR-UHFFFAOYSA-N UPP1 GeneProduct ncbigene:7378 ensembl:ENSG00000183696 ncbigene:7378 hgnc.symbol:UPP1 uniprot:C9J486;uniprot:B4DND0;uniprot:Q16831;uniprot:F8WD51;uniprot:C9JIP2;uniprot:C9K0J2 TK1 GeneProduct ncbigene:7083 ensembl:ENSG00000167900 ncbigene:7083 hgnc.symbol:TK1 uniprot:A0A384MDV9;uniprot:K7ES52;uniprot:K7ERV3;uniprot:K7ENW5;uniprot:P04183;uniprot:K7ERJ1 SLC22A7 GeneProduct ncbigene:10864 ensembl:ENSG00000137204 ncbigene:10864 hgnc.symbol:SLC22A7 uniprot:Q5T051;uniprot:Q9Y694;uniprot:X6RDF7;uniprot:Q5T047 ABCC5 GeneProduct ncbigene:10057 ensembl:ENSG00000114770 ncbigene:10057 hgnc.symbol:ABCC5 uniprot:H7C271;uniprot:O15440;uniprot:E9PET4;uniprot:C9JZL5;uniprot:A5PKY6;uniprot:F8WDH3;uniprot:F8WCY8 DHFR GeneProduct ncbigene:1719 ensembl:ENSG00000228716 ncbigene:1719 hgnc.symbol:DHFR uniprot:B4DM58;uniprot:B0YJ76;uniprot:P00374 CDA GeneProduct ncbigene:978 ensembl:ENSG00000158825 ncbigene:978 hgnc.symbol:CDA uniprot:P32320 TDG GeneProduct ncbigene:6996 ensembl:ENSG00000139372 ncbigene:6996 hgnc.symbol:TDG uniprot:H0YH18;uniprot:Q13569;uniprot:F5H539;uniprot:G8JL98;uniprot:F5H0I7;uniprot:B4E127 ABCC3 GeneProduct ncbigene:8714 ensembl:ENSG00000108846 ncbigene:8714 hgnc.symbol:ABCC3 uniprot:D6RJE5;uniprot:H0Y8Q6;uniprot:O15438;uniprot:H0Y8T5;uniprot:H0Y9T4;uniprot:D6RAB7 UPP2 GeneProduct ncbigene:151531 ensembl:ENSG00000007001 ncbigene:151531 hgnc.symbol:UPP2 uniprot:A0A0S2Z634;uniprot:O95045 DPYD GeneProduct ncbigene:1806 ensembl:ENSG00000188641 ncbigene:1806 hgnc.symbol:DPYD uniprot:Q12882 MIR29C GeneProduct ensembl:ENSG00000284214 ensembl:ENSG00000284214 ncbigene:407026 hgnc.symbol:MIR29C UPP1 GeneProduct ncbigene:7378 ensembl:ENSG00000183696 ncbigene:7378 hgnc.symbol:UPP1 uniprot:C9J486;uniprot:B4DND0;uniprot:Q16831;uniprot:F8WD51;uniprot:C9JIP2;uniprot:C9K0J2 FPGS GeneProduct ncbigene:2356 ensembl:ENSG00000136877 ncbigene:2356 hgnc.symbol:FPGS uniprot:Q5JU21;uniprot:Q5JU20;uniprot:Q5JU23;uniprot:Q05932 ABCC4 GeneProduct ncbigene:10257 ensembl:ENSG00000125257 ncbigene:10257 hgnc.symbol:ABCC4 uniprot:A0A2R8Y5Z3;uniprot:Q8IWU1;uniprot:A0A2R8YDC1;uniprot:A0A2R8YDG7;uniprot:O15439;uniprot:A0A2R8Y6V8 SMUG1 GeneProduct ncbigene:23583 ensembl:ENSG00000123415 ncbigene:23583 hgnc.symbol:SMUG1 uniprot:D6RIA4;uniprot:A0A0U1RRE6;uniprot:D6RAI1;uniprot:A0A024RAZ8;uniprot:A0A0S2Z526;uniprot:D6RAS0;uniprot:H0YA95;uniprot:D6RI04;uniprot:Q53HV7;uniprot:D6RA25;uniprot:D6RD88;uniprot:D6RA78 TYMS GeneProduct ncbigene:7298 ensembl:ENSG00000176890 ncbigene:7298 hgnc.symbol:TYMS uniprot:P04818;uniprot:Q53Y97 TYMP GeneProduct ncbigene:1890 ensembl:ENSG00000025708 ncbigene:1890 hgnc.symbol:TYMP uniprot:A0A494C0A4;uniprot:C9JGI3;uniprot:A0A494BZZ4;uniprot:P19971;uniprot:A0A494C1L9;uniprot:E5KRG5;uniprot:A0A494C0L3;uniprot:A0A494C0L6;uniprot:A0A494C1N7 MTHFR GeneProduct ncbigene:4524 ensembl:ENSG00000177000 ncbigene:4524 hgnc.symbol:MTHFR uniprot:A0A286YF17;uniprot:Q5SNW5;uniprot:P42898;uniprot:Q5SNW7;uniprot:F8W9T8;uniprot:A0A286YFD0;uniprot:A0A286YF47;uniprot:A0A1B0GXD9;uniprot:L7P8G6 DPYS GeneProduct ncbigene:1807 ensembl:ENSG00000147647 ncbigene:1807 hgnc.symbol:DPYS uniprot:Q14117;uniprot:E5RG28;uniprot:H0YEV7 RRM1 GeneProduct ncbigene:6240 ensembl:ENSG00000167325 ncbigene:6240 hgnc.symbol:RRM1 uniprot:H0YCY7;uniprot:E9PJ62;uniprot:E9PL69;uniprot:E9PP77;uniprot:P23921;uniprot:E9PRY9 UMPS GeneProduct ncbigene:7372 ensembl:ENSG00000114491 ncbigene:7372 hgnc.symbol:UMPS uniprot:A8K5J1;uniprot:F2Z3P2;uniprot:F2Z303;uniprot:F8WDG4;uniprot:P11172;uniprot:E9PFD2 UCK1 GeneProduct ncbigene:83549 ensembl:ENSG00000130717 ncbigene:83549 hgnc.symbol:UCK1 uniprot:Q9HA47;uniprot:G3V170;uniprot:A0A024R8E7 XRCC3 GeneProduct ncbigene:7517 ensembl:ENSG00000126215 ncbigene:7517 hgnc.symbol:XRCC3 uniprot:O43542;uniprot:G3V2L7;uniprot:Q53XC8;uniprot:G3V3H9;uniprot:G3V3Q2;uniprot:G3V399;uniprot:G3V2P3;uniprot:G3V3C8;uniprot:G3V5K0 ERCC2 GeneProduct ncbigene:2068 ensembl:ENSG00000104884 ncbigene:2068 hgnc.symbol:ERCC2 uniprot:B4E0F6;uniprot:K7EIT8;uniprot:P18074;uniprot:A8MX75;uniprot:K7EKF3;uniprot:E7EVE9;uniprot:K7ENL1 CES1 GeneProduct ncbigene:1066 ensembl:ENSG00000198848 ncbigene:1066 hgnc.symbol:CES1 uniprot:P23141;uniprot:H3BQR4;uniprot:H3BQV8;uniprot:H3BSU0 UCK2 GeneProduct ncbigene:7371 ensembl:ENSG00000143179 ncbigene:7371 hgnc.symbol:UCK2 uniprot:Q9BZX2;uniprot:A0A2R8Y653 GGH GeneProduct ncbigene:8836 ensembl:ENSG00000137563 ncbigene:8836 hgnc.symbol:GGH uniprot:Q92820 CYP2A6 GeneProduct ncbigene:1548 ensembl:ENSG00000255974 ncbigene:1548 hgnc.symbol:CYP2A6 uniprot:P11509;uniprot:M0R2Z4 ABCG2 GeneProduct ncbigene:9429 ensembl:ENSG00000118777 ncbigene:9429 hgnc.symbol:ABCG2 uniprot:A1LUE4;uniprot:Q9UNQ0;uniprot:F8S0F2 TP53 GeneProduct ncbigene:7157 ensembl:ENSG00000141510 ncbigene:7157 hgnc.symbol:TP53 uniprot:E9PFT5;uniprot:A0A087WXZ1;uniprot:P04637;uniprot:A0A087X1Q1;uniprot:E7ESS1;uniprot:E7EMR6;uniprot:E7EQX7;uniprot:A0A0U1RQC9;uniprot:J3KP33;uniprot:H2EHT1;uniprot:I3L0W9;uniprot:K7PPA8;uniprot:S4R334;uniprot:A0A087WT22;uniprot:E9PCY9 RRM2 GeneProduct ncbigene:6241 ensembl:ENSG00000171848 ncbigene:6241 hgnc.symbol:RRM2 uniprot:A0A2R8Y837;uniprot:P31350;uniprot:A0A286YFD6 SLC29A1 GeneProduct ncbigene:2030 ensembl:ENSG00000112759 ncbigene:2030 hgnc.symbol:SLC29A1 uniprot:A0A2U3TZJ7;uniprot:A0A2R8YFB9;uniprot:A0A2R8Y6D1;uniprot:A0A2R8YFI6;uniprot:Q99808;uniprot:A0A2R8Y854;uniprot:A0A2R8Y567;uniprot:A0A2R8YEH8;uniprot:A0A2U3TZM5;uniprot:A0A2U3TZM6;uniprot:A0A2R8Y801 UPB1 GeneProduct ncbigene:51733 ensembl:ENSG00000100024 ncbigene:51733 hgnc.symbol:UPB1 uniprot:A0A024R1H3;uniprot:Q9UBR1;uniprot:Q6AHZ8;uniprot:F8WC94 UPP2 GeneProduct ncbigene:151531 ensembl:ENSG00000007001 ncbigene:151531 hgnc.symbol:UPP2 uniprot:A0A0S2Z634;uniprot:O95045 TYMP GeneProduct ncbigene:1890 ensembl:ENSG00000025708 ncbigene:1890 hgnc.symbol:TYMP uniprot:A0A494C0A4;uniprot:C9JGI3;uniprot:A0A494BZZ4;uniprot:P19971;uniprot:A0A494C1L9;uniprot:E5KRG5;uniprot:A0A494C0L3;uniprot:A0A494C0L6;uniprot:A0A494C1N7 PPAT GeneProduct ncbigene:5471 ensembl:ENSG00000128059 ncbigene:5471 hgnc.symbol:PPAT uniprot:D6RE15;uniprot:Q06203;uniprot:A8K4H7;uniprot:D6RCC8 ABCC4 GeneProduct ncbigene:10257 ensembl:ENSG00000125257 ncbigene:10257 hgnc.symbol:ABCC4 uniprot:A0A2R8Y5Z3;uniprot:Q8IWU1;uniprot:A0A2R8YDC1;uniprot:A0A2R8YDG7;uniprot:O15439;uniprot:A0A2R8Y6V8 CES2 GeneProduct ncbigene:8824 ensembl:ENSG00000172831 ncbigene:8824 hgnc.symbol:CES2 uniprot:O00748;uniprot:H3BUN5;uniprot:J3QSC0;uniprot:J3QLP1