Label Type Identifier Comment Ensembl NCBI gene HGNC UniProt Wikidata ChEBI InChI PubChem ChemSpider HMDB KEGG LipidMaps Gamma-aminobutanoic acid (GABA) Metabolite chebi:59888 "aka gamma-aminobutyric acid" wikidata:Q106345483;wikidata:Q210021 chebi:16865;chebi:59888 inchikey:BTCSSZJGUNDROE-UHFFFAOYSA-N pubchem.compound:6992099;pubchem.compound:119 chemspider:116 hmdb:HMDB0000112 kegg.compound:C00334 lipidmaps:LMFA01100039 succinic acid Metabolite chebi:30031 "aka succinate" wikidata:Q27104100 chebi:30031 inchikey:KDYFGRWQOYBRFD-UHFFFAOYSA-L pubchem.compound:160419 chemspider:140973 N-acetylputrescine Metabolite chebi:17768 "" wikidata:Q27102595 chebi:17768 inchikey:KLZGKIDSEJWEDW-UHFFFAOYSA-N pubchem.compound:122356 chemspider:109095 hmdb:HMDB0002064 kegg.compound:C02714 4,5-dihydroxyhexanoic acid lactone Metabolite hmdb:HMDB0002173 "AKA Solerol, ring-structure, appears to ba a biomarker for SSADH deficiency [PMID:3126356]" chebi:89760 inchikey:QFCPIZSGDXQFDK-UHFFFAOYSA-N pubchem.compound:21252275 chemspider:13628309 hmdb:HMDB0002173 4-butyrolactone Metabolite chebi:42639 "" wikidata:Q79739 chebi:42639 inchikey:YEJRWHAVMIAJKC-UHFFFAOYSA-N pubchem.compound:7302 chemspider:7029 hmdb:HMDB0000549 kegg.compound:C01770 lipidmaps:LMFA07040004 D-2-hydroxyglutaric acid Metabolite chebi:15801 "aka D-2-hydroxyglutarate" wikidata:Q27098238 chebi:15801 inchikey:HWXBTNAVRSUOJR-GSVOUGTGSA-L pubchem.compound:5460200 chemspider:4573827 kegg.compound:C01087 Gamma-hydroxybutyric acid (GHB) Metabolite chebi:16724 "aka 4-hydroxybutanoic acid, Gamma-Hydroxybutyrate" wikidata:Q60998674 chebi:16724 inchikey:SJZRECIVHVDYJC-UHFFFAOYSA-M pubchem.compound:3037032 kegg.compound:C00989 Homocarnosine Metabolite chebi:85981 "" wikidata:Q27158831;wikidata:Q106314674 chebi:85981;chebi:143075 inchikey:CCLQKVKJOGVQLU-QMMMGPOBSA-N pubchem.compound:10243361 chemspider:8418848 hmdb:HMDB0000745 kegg.compound:C00884 1,4-butanediol Metabolite chebi:41189 "" wikidata:Q161521 chebi:41189 inchikey:WERYXYBDKMZEQL-UHFFFAOYSA-N pubchem.compound:8064 chemspider:13835209 hmdb:HMDB0244201 N-acetyl gamma-aminobutyraldehyde Metabolite pubchem.compound:440850 "AKA 4-Acetamidobutanal" wikidata:Q27107484 chebi:7386 inchikey:DDSLGZOYEPKPSJ-UHFFFAOYSA-N pubchem.compound:440850 chemspider:389692 hmdb:HMDB0004226 kegg.compound:C05936 3-oxo-4-hydroxybutyric acid Metabolite pubchem.compound:19793911 "aka 4-hydroxy-3-oxobutanoic acid" wikidata:Q45435230 inchikey:JEZCMVCLPKSUOT-UHFFFAOYSA-N pubchem.compound:19793911 N-acetyl gamma-aminobutyrate Metabolite pubchem.compound:18189 "AKA 4-Acetamidobutyric acid" wikidata:Q27102497 chebi:17645 inchikey:UZTFMUBKZQVKLK-UHFFFAOYSA-N pubchem.compound:18189 chemspider:17180 hmdb:HMDB0003681 kegg.compound:C02946 4-hydroxybutyraldehyde Metabolite pubchem.compound:93093 "aka 4-hydroxybutanal" wikidata:Q19597550 inchikey:PIAOXUVIBAKVSP-UHFFFAOYSA-N pubchem.compound:93093 chemspider:84042 Putrescine Metabolite chebi:17148 "" wikidata:Q410190 chebi:17148 inchikey:KIDHWZJUCRJVML-UHFFFAOYSA-N pubchem.compound:1045 chemspider:13837702 hmdb:HMDB0001414 kegg.compound:C02896;kegg.compound:C00134 Alpha-ketoglutarate Metabolite chebi:16810 "aka 2-ketoglutarate aka 2-oxoglutarate" wikidata:Q27102088 chebi:16810 inchikey:KPGXRSRHYNQIFN-UHFFFAOYSA-L pubchem.compound:164533 chemspider:144236 kegg.compound:C00026 Glycolic acid Metabolite chebi:17497 "" wikidata:Q409373 chebi:17497 inchikey:AEMRFAOFKBGASW-UHFFFAOYSA-N pubchem.compound:757 chemspider:737 hmdb:HMDB0000115 kegg.compound:C03547;kegg.compound:C00160 lipidmaps:LMFA01050148 3,4-dihydroxybutyric acid Metabolite chebi:86371 "" wikidata:Q27159112 chebi:86371 inchikey:DZAIOXUZHHTJKN-UHFFFAOYSA-N pubchem.compound:150929 chemspider:133026 hmdb:HMDB0000337 lipidmaps:LMFA01050461 PLP Metabolite chebi:18405 "AKA Pyridoxal phosphate, pyridoxal 5'-phosphate, P5P" wikidata:Q418957 chebi:18405 inchikey:NGVDGCNFYWLIFO-UHFFFAOYSA-N pubchem.compound:1051 chemspider:1022 hmdb:HMDB0001491 kegg.compound:C00018 Glutamine Metabolite chebi:58359 "" wikidata:Q106345471;wikidata:Q181619 chebi:18050;chebi:58359 inchikey:ZDXPYRJPNDTMRX-VKHMYHEASA-N pubchem.compound:5961;pubchem.compound:6992086 chemspider:5746 hmdb:HMDB0000641 kegg.compound:C00064 Succinic semialdehyde Metabolite chebi:57706 "" wikidata:Q27073958 chebi:57706 inchikey:UIUJIQZEACWQSV-UHFFFAOYSA-M pubchem.compound:9543238 chemspider:7822211 Glutamic acid Metabolite chebi:16015 "AKA glutamate" wikidata:Q26995161 chebi:16015 inchikey:WHUUTDBJXJRKMK-VKHMYHEASA-N pubchem.compound:44272391;pubchem.compound:88747398;pubchem.compound:33032 chemspider:30572 hmdb:HMDB0000148 kegg.compound:C00025 Uracil Metabolite chebi:17568 "" wikidata:Q182990 chebi:17568 inchikey:ISAKRJDGNUQOIC-UHFFFAOYSA-N pubchem.compound:1174 chemspider:1141 hmdb:HMDB0000300 kegg.compound:C00106 Beta-alanine Metabolite chebi:16958 "" wikidata:Q106345620;wikidata:Q310919 chebi:16958;chebi:57966 inchikey:UCMIRNVEIXFBKS-UHFFFAOYSA-N pubchem.compound:239;pubchem.compound:4755801 chemspider:234 hmdb:HMDB0000056 kegg.compound:C00099 Malonic semialdehyde Metabolite chebi:17960 "" wikidata:Q27102737 chebi:17960 inchikey:OAKURXIZZOAYBC-UHFFFAOYSA-N pubchem.compound:868 chemspider:845 hmdb:HMDB0011111 kegg.compound:C00222 4,5-dihydroxyhexanoic acid Metabolite hmdb:HMDB0240745 "AKA DHHA, open-structure, appears to ba a biomarker for SSADH deficiency [PMID:3126356]" wikidata:Q113495228 inchikey:FKHCKVQMPWUKCV-UHFFFAOYSA-N pubchem.compound:57417380 chemspider:60645551 hmdb:HMDB0240745 4-hydroxybutyric acid Metabolite chebi:30830 "" wikidata:Q72498582;wikidata:Q207920 chebi:30830 inchikey:SJZRECIVHVDYJC-UHFFFAOYSA-N pubchem.compound:10413 chemspider:9984 hmdb:HMDB0000710 kegg.compound:C00989;kegg.compound:C01991 lipidmaps:LMFA01050006 3-oxo-4-hydroxybutanoic Metabolite pubchem.compound:19793911 "aka 3-oxo-4-hydroxybutyric acid aka 4-hydroxy-3-oxobutanoic acid" wikidata:Q45435230 inchikey:JEZCMVCLPKSUOT-UHFFFAOYSA-N pubchem.compound:19793911 2-oxo-4-hydroxybutanoic Metabolite chebi:173437 "aka 2-oxo-4-hydroxybutyric acid aka 4-hydroxy-2-oxobutanoic acid" wikidata:Q27467050 chebi:173437 inchikey:PUWWONYMIXRVQF-UHFFFAOYSA-N pubchem.compound:11963036 chemspider:10137246 hmdb:HMDB0031204 3-hydroxypropionic Metabolite chebi:33404 "aka 3-hydroxypropionic acid" wikidata:Q2823220 chebi:33404 inchikey:ALRHLSYJTWAHJZ-UHFFFAOYSA-N pubchem.compound:68152 chemspider:61460 hmdb:HMDB0000700 kegg.compound:C01013 lipidmaps:LMFA01050003 2-ketoglutarate Metabolite chebi:16810 "" wikidata:Q27102088 chebi:16810 inchikey:KPGXRSRHYNQIFN-UHFFFAOYSA-L pubchem.compound:164533 chemspider:144236 kegg.compound:C00026 D-2-hydroxyglutarate Metabolite chebi:15801 "D-2-hydroxyglutaric acid" wikidata:Q27098238 chebi:15801 inchikey:HWXBTNAVRSUOJR-GSVOUGTGSA-L pubchem.compound:5460200 chemspider:4573827 kegg.compound:C01087 GAD Protein eccode:4.1.1.15 "AKA Glutamic acid decarboxylase, exists in two isoforms with molecular weights of 67 and 65 kDa (GAD67 and GAD65), encoded by two different genes (GAD1 and GAD2)" D-2-hydroxyglutarate transhydrogenase Protein uniprot:Q8IWW8 "aka hydroxyacid-oxoacid transhydrogenase (HOT)" ensembl:ENSG00000147576 ncbigene:137872 hgnc.symbol:ADHFE1 uniprot:F2Z3E5;uniprot:F2Z2N0;uniprot:Q8IWW8;uniprot:F2Z3D8;uniprot:B4DV11;uniprot:B4DFI7 Glutaminase Protein eccode:3.5.1.2 "Glutaminase has tissue-specific isoenzymes and 4 isoforms: the GLS gene encodes 2 types (active in kidney, and the GLS2 gene encodes 2 forms (active in liver)" ADH Protein eccode:1.1.1.1 "alcohol dehydrogenase; Wikidata:Q410754" Serum paraoxonase/lactonase 3 (b) Protein eccode:3.1.1.81 "" GHB dehydro-genase Protein eccode:1.1.1.61 "aka NAD-dependent 4-hydroxybutyrate dehydrogenase" MAOB Protein uniprot:P27338 "" ensembl:ENSG00000069535 ncbigene:4129 hgnc.symbol:MAOB uniprot:P27338 ALDH Protein eccode:1.2.1.3 "aldehyde dehydrogenase" SSA reductase Protein uniprot:O43488 "" ensembl:ENSG00000053371 ncbigene:8574 hgnc.symbol:AKR7A2 uniprot:H7C4Q7;uniprot:O43488;uniprot:H7C5H7;uniprot:H3BLU7;uniprot:V9HWA2 GABAT Protein uniprot:P80404 "GABA transaminase" ensembl:ENSG00000183044 ncbigene:18 hgnc.symbol:ABAT uniprot:H3BNQ7;uniprot:H3BPW8;uniprot:X5D8S1;uniprot:H3BP74;uniprot:H3BMJ9;uniprot:H3BP84;uniprot:H3BRT1;uniprot:H3BRJ1;uniprot:H3BRN4;uniprot:P80404 Serum paraoxonase/lactonase 3 (c) Protein eccode:3.1.1.2 "" GAD1 Protein uniprot:Q99259 "AKA GAD67" ensembl:ENSG00000128683 ncbigene:2571 hgnc.symbol:GAD1 uniprot:C9JT43;uniprot:U3KQR2;uniprot:C9JN45;uniprot:C9JLZ7;uniprot:C9J6C9;uniprot:A0A0S2Z3V5;uniprot:Q99259;uniprot:F8WD43 Lactamase Protein uniprot:P16444 "" ensembl:ENSG00000015413 ncbigene:1800 hgnc.symbol:DPEP1 uniprot:H3BQS5;uniprot:A0A140VJI3;uniprot:H3BP43;uniprot:P16444 GLS (kidney) Protein uniprot:O94925 "" ensembl:ENSG00000115419 ncbigene:2744 hgnc.symbol:GLS uniprot:A0A994J3S8;uniprot:B8ZZC5;uniprot:H7BZD1;uniprot:H7C201;uniprot:B7Z509;uniprot:O94925 Homocarnosinase/carnosinase Protein eccode:3.4.13.3 "" Serum paraoxonase/lactonase 3 (a) Protein eccode:3.1.8.1 "" SSADH Protein uniprot:P51649 "Succinate-semialdehyde dehydrogenase" ensembl:ENSG00000112294 ncbigene:7915 hgnc.symbol:ALDH5A1 uniprot:A0A5F9ZH98;uniprot:X5DQN2;uniprot:P51649;uniprot:A0A5F9ZI23;uniprot:A0A5F9ZH05;uniprot:C9J8Q5;uniprot:X5D299 Serum paraoxonase/lactonase 3 Protein uniprot:Q15166 "" ensembl:ENSG00000105852 ncbigene:5446 hgnc.symbol:PON3 uniprot:C9JZ99;uniprot:F8WD41;uniprot:F8WBV4;uniprot:F2Z2L3;uniprot:Q15166 GLS2 (liver) Protein uniprot:Q9UI32 "" ensembl:ENSG00000135423 ncbigene:27165 hgnc.symbol:GLS2 uniprot:F8WBC9;uniprot:C9J3Q2;uniprot:F8WEU7;uniprot:A8K0A6;uniprot:A0A087X004;uniprot:F8WBL8;uniprot:G5E9X4;uniprot:Q9UI32;uniprot:E5G745 GAD2 Protein uniprot:Q05329 "AKA GAD65" ensembl:ENSG00000136750 ncbigene:2572 hgnc.symbol:GAD2 uniprot:A0A3B3IU09;uniprot:Q5VZ30;uniprot:Q05329;uniprot:Q5VZ31