Label Type Identifier Comment Ensembl NCBI gene HGNC UniProt Wikidata ChEBI InChI PubChem ChemSpider HMDB KEGG LipidMaps Dihydrotestosterone Metabolite chebi:16330 "" wikidata:Q411054 chebi:16330 inchikey:NVKAWKQGWWIWPM-ABEVXSGRSA-N pubchem.compound:10635 chemspider:10189 hmdb:HMDB0002961 kegg.compound:C03917 lipidmaps:LMST02020042 Testosterone Metabolite chebi:17347 "" wikidata:Q1318776 chebi:17347 inchikey:MUMGGOZAMZWBJJ-DYKIIFRCSA-N pubchem.compound:6013 chemspider:5791 hmdb:HMDB0000234 kegg.compound:C00535 lipidmaps:LMST02020002 Oestradiol Metabolite chebi:16469 "" wikidata:Q422416 chebi:16469 inchikey:VOXZDWNPVJITMN-ZBRFXRBCSA-N pubchem.compound:5757 chemspider:5554 hmdb:HMDB0000151 kegg.compound:C00951 lipidmaps:LMST02010001 Cholesterol Metabolite chebi:16113 "" wikidata:Q43656 chebi:16113 inchikey:HVYWMOMLDIMFJA-DPAQBDIFSA-N pubchem.compound:5997 chemspider:5775 hmdb:HMDB0000067 kegg.compound:C00187 lipidmaps:LMST01010001 17-hydroxyprogesterone Metabolite chebi:17252 "" wikidata:Q175901 chebi:17252 inchikey:DBPWSSGDRRHUNT-CEGNMAFCSA-N pubchem.compound:6238 chemspider:6002 hmdb:HMDB0000374 kegg.compound:C01176 lipidmaps:LMST02030161 Cortisone Metabolite chebi:16962 "" wikidata:Q423185 chebi:16962 inchikey:MFYSYFVPBJMHGN-ZPOLXVRWSA-N pubchem.compound:222786 chemspider:193441 hmdb:HMDB0002802 kegg.compound:C00762 lipidmaps:LMST02030090 Progesterone Metabolite chebi:17026 "" wikidata:Q26963 chebi:17026 inchikey:RJKFOVLPORLFTN-LEKSSAKUSA-N pubchem.compound:5994 chemspider:5773 hmdb:HMDB0001830 kegg.compound:C00410 lipidmaps:LMST02030159 Corticosterone Metabolite chebi:16827 "" wikidata:Q422543 chebi:16827 inchikey:OMFXVFTZEKFJBZ-HJTSIMOOSA-N pubchem.compound:5753 chemspider:5550 hmdb:HMDB0001547 kegg.compound:C02140 lipidmaps:LMST02030186 11-Deoxycortisol Metabolite chebi:28324 "" wikidata:Q2064915 chebi:28324 inchikey:WHBHBVVOGNECLV-OBQKJFGGSA-N pubchem.compound:440707 chemspider:389582 hmdb:HMDB0000015 kegg.compound:C05488 lipidmaps:LMST02030086 DHEA Metabolite chebi:28689 "" wikidata:Q408376 chebi:28689 inchikey:FMGSKLZLMKYGDP-USOAJAOKSA-N pubchem.compound:5881 chemspider:8036443;chemspider:5670 hmdb:HMDB0000077 kegg.compound:C01227 lipidmaps:LMST02020021 Cortisol Metabolite wikidata:Q190875 "" wikidata:Q190875 chebi:17650 inchikey:JYGXADMDTFJGBT-VWUMJDOOSA-N pubchem.compound:5754 chemspider:5551 hmdb:HMDB0000063 kegg.compound:C00735 lipidmaps:LMST02030001 Androstenedione Metabolite chebi:16422 "" wikidata:Q411064 chebi:16422 inchikey:AEMFNILZOJDQLW-QAGGRKNESA-N pubchem.compound:6128 chemspider:5898 hmdb:HMDB0000053 kegg.compound:C00280 lipidmaps:LMST02020007 (11)-Deoxycorticosterone Metabolite chebi:16973 "" wikidata:Q948846 chebi:16973 inchikey:ZESRJSPZRDMNHY-YFWFAHHUSA-N pubchem.compound:6166 chemspider:5932 hmdb:HMDB0000016 kegg.compound:C03205 lipidmaps:LMST02030087 18-hydroxycorticosterone Metabolite chebi:16485 "" wikidata:Q3597767 chebi:16485 inchikey:HFSXHZZDNDGLQN-ZVIOFETBSA-N pubchem.compound:11222 chemspider:10748 hmdb:HMDB0000319 kegg.compound:C01124 lipidmaps:LMST02030091 Aldosterone Metabolite chebi:27584 "" wikidata:Q184564 chebi:27584 inchikey:PQSUYGKTWSAVDQ-ZVIOFETBSA-N pubchem.compound:5839 chemspider:5633 hmdb:HMDB0000037 kegg.compound:C01780 lipidmaps:LMST02030026 17-hydroxypregnenolone Metabolite chebi:28750 "" wikidata:Q35666789 chebi:28750 inchikey:JERGUCIJOXJXHF-TVWVXWENSA-N pubchem.compound:91451 chemspider:82579;chemspider:217096 hmdb:HMDB0000363 kegg.compound:C05138 lipidmaps:LMST02030089 Pregnenolone Metabolite chebi:16581 "" wikidata:Q412158 chebi:16581 inchikey:ORNBQBCIOKFOEO-QGVNFLHTSA-N pubchem.compound:8955 chemspider:8611 hmdb:HMDB0000253 kegg.compound:C01953 lipidmaps:LMST02030088 NADP+ Metabolite chebi:58349 "" wikidata:Q27125717 chebi:58349 inchikey:XJLXINKUBYWONI-NNYOXOHSSA-K pubchem.compound:15938972 chemspider:10239198 NADPH Metabolite chebi:57783 "" wikidata:Q27124944 chebi:57783 inchikey:ACFIXJIJDZMPPO-NNYOXOHSSA-J pubchem.compound:15983949 chemspider:10239199 11b, 21-Dihydroxy-3,20-5b-Pregnan-18-al Metabolite pubchem.compound:44263338 "" wikidata:Q101432284 chebi:171688 inchikey:IIBOWSHDTFRYKU-AGSIWSQZSA-N pubchem.compound:44263338 lipidmaps:LMST02030187 3a,11b,21-Trihydroxy-20-Oxo-5b-Pregnan-18-al Metabolite pubchem.compound:44263346 "" wikidata:Q101432287 chebi:171956 inchikey:YWTDWORQGPLRLL-CVPRMUEYSA-N pubchem.compound:44263346 lipidmaps:LMST02030197 3a-OH-5b-Pregnane-20-one Metabolite pubchem.compound:24779614 "" wikidata:Q27160720 chebi:88767 inchikey:ZDUVZJUTJOBJHS-HNEBDTNWSA-N;inchikey:AURFZBICLPNKBZ-KCZNCWLVSA-N pubchem.compound:24779614 chemspider:23141070 hmdb:HMDB0006756;hmdb:HMDB0006759 kegg.compound:C05480 5b-Pregnane-3,20-dione Metabolite pubchem.compound:92745 "" wikidata:Q21099648 chebi:30154 inchikey:XMRPGKVKISIQBV-XWOJZHJZSA-N pubchem.compound:92745 chemspider:83723 hmdb:HMDB0304221 kegg.compound:C05479 lipidmaps:LMST02030146 Pregnanediol Metabolite cas:80-92-2 "" wikidata:Q906054 chebi:8387 inchikey:YWYQTGBBEZQBGO-BERLURQNSA-N pubchem.compound:219833 chemspider:190585 hmdb:HMDB0004025 kegg.compound:C05484 lipidmaps:LMST02030264 Glucuronides Metabolite chebi:26763 "" wikidata:Q137786 chebi:26763 17a,21-Dihydroxy-5b-17a,21-Dihydroxy-5b-Pregnane-3,11,20-trione Metabolite pubchem.compound:65554 "aka 4,5beta-Dihydrocortisone" wikidata:Q5276425 chebi:18093 inchikey:YCLWEYIBFOLMEM-FNLRALKVSA-N pubchem.compound:65554 chemspider:58997 hmdb:HMDB0006758 kegg.compound:C05469 lipidmaps:LMST02030095 Urocortisone Metabolite pubchem.compound:5754 "" wikidata:Q190875 chebi:17650 inchikey:JYGXADMDTFJGBT-VWUMJDOOSA-N pubchem.compound:5754 chemspider:5551 hmdb:HMDB0000063 kegg.compound:C00735 lipidmaps:LMST02030001 Cortolone Metabolite cas:516-42-7 "" wikidata:Q27106233 chebi:3899 inchikey:JXCOSKURGJMQSG-AZQJGLEESA-N pubchem.compound:160499 chemspider:141038 hmdb:HMDB0003128 kegg.compound:C05481 lipidmaps:LMST02030227 Urocortisol Metabolite pubchem.compound:5864 "AKA Tetrahydrocortisol" wikidata:Q7706545 chebi:28320 inchikey:AODPIQQILQLWGS-GXBDJPPSSA-N pubchem.compound:5864 chemspider:5655 hmdb:HMDB0000949 kegg.compound:C05472 lipidmaps:LMST02030143 11b,17a 21-Trihydroxy-5bPregnane 3,20-dione Metabolite cas:1482-50-4 "AKA 11-BETA,17-ALPHA,21-TRIHYDROXY-5-BETA-PREGNANE-3,20-DIONE" wikidata:Q27105345 chebi:732 inchikey:ACSFOIGNUQUIGE-AIPUTVCKSA-N pubchem.compound:164838 chemspider:144508 hmdb:HMDB0003259 kegg.compound:C05471 lipidmaps:LMST02030204 CYP11A1 GeneProduct ncbigene:1583 "" ensembl:ENSG00000140459 ncbigene:1583 hgnc.symbol:CYP11A1 uniprot:P05108;uniprot:C9JPU9;uniprot:H3BS93;uniprot:A0A0S2Z3R3;uniprot:C9JXV4;uniprot:E7EPP8;uniprot:H3BSZ1 HSD3B1 GeneProduct ncbigene:3283 "" ensembl:ENSG00000203857 ncbigene:3283 hgnc.symbol:HSD3B1 uniprot:E9PRN7;uniprot:P14060 HSD3B2 GeneProduct ncbigene:3284 "" ensembl:ENSG00000203859 ncbigene:3284 hgnc.symbol:HSD3B2 uniprot:P26439;uniprot:A0A024R0F9;uniprot:Q5QP01 CYP11B2 GeneProduct ncbigene:1585 "" ensembl:ENSG00000179142 ncbigene:1585 hgnc.symbol:CYP11B2 uniprot:P19099 Corticosterone methyl oxidase Protein ensembl:ENSG00000179142 "" ensembl:ENSG00000179142 ncbigene:1585 hgnc.symbol:CYP11B2 uniprot:P19099 P450scc Protein ensembl:ENSG00000140459 "also known as CYP11A1" ensembl:ENSG00000140459 ncbigene:1583 hgnc.symbol:CYP11A1 uniprot:P05108;uniprot:C9JPU9;uniprot:H3BS93;uniprot:A0A0S2Z3R3;uniprot:C9JXV4;uniprot:E7EPP8;uniprot:H3BSZ1 P450c21 Protein ensembl:ENSG00000231852 "" ensembl:ENSG00000231852 ncbigene:1589 hgnc.symbol:CYP21A2 uniprot:E7EN87;uniprot:E7EVC0;uniprot:E7ERT7;uniprot:Q16874;uniprot:F8WBR4;uniprot:P08686 11beta-HSD1 Protein ensembl:ENSG00000117594 "Reference study in mice [PMID:9405715]" ensembl:ENSG00000117594 ncbigene:3290 hgnc.symbol:HSD11B1 uniprot:P28845;uniprot:X5D2L1;uniprot:A0A087WU76;uniprot:A0A0A0MQV1 3-beta-HSD Protein ensembl:ENSG00000203859 "" ensembl:ENSG00000203859 ncbigene:3284 hgnc.symbol:HSD3B2 uniprot:P26439;uniprot:A0A024R0F9;uniprot:Q5QP01 STAR Protein ensembl:ENSG00000147465 "" ensembl:ENSG00000147465 ncbigene:6770 hgnc.symbol:STAR uniprot:P49675;uniprot:E5RH12;uniprot:Q6IBK0;uniprot:H0YB94 11beta-HSD2 Protein ensembl:ENSG00000176387 "" ensembl:ENSG00000176387 ncbigene:3291 hgnc.symbol:HSD11B2 uniprot:R4GN04;uniprot:P80365 POR Protein uniprot:P16435 "" ensembl:ENSG00000127948 ncbigene:5447 hgnc.symbol:POR uniprot:C9JQ78;uniprot:C9JDE2;uniprot:A0A8V8PBF2;uniprot:C9JU80;uniprot:A0A8V8NRY5;uniprot:A0A8V8NE24;uniprot:A0A8V8NLF0;uniprot:A0A8V8NKH1;uniprot:P16435;uniprot:A0A8V8P1G2;uniprot:A0A8V8NVX2;uniprot:A0A8V8NVY2;uniprot:E7EWU0;uniprot:A0A8V8P672;uniprot:E7EMD0;uniprot:H0Y4R2 17-beta-HSD3 Protein ensembl:ENSG00000130948 "" ensembl:ENSG00000130948 ncbigene:3293 hgnc.symbol:HSD17B3 uniprot:A0A3B3ITW2;uniprot:P37058;uniprot:A0A0S2Z406;uniprot:A0A0S2Z413;uniprot:Q6FH62;uniprot:A0A0S2Z3U6;uniprot:A0A0S2Z3V7;uniprot:A0A3B3ITT4 H6PD Protein ensembl:ENSG00000049239 "This enzyme produces NADPH which is neccessary for 11beta-HSD1 to convert cortisone into cortisol." ensembl:ENSG00000049239 ncbigene:9563 hgnc.symbol:H6PD uniprot:O95479 Cytochrome b5 Protein uniprot:J3KNC7 "" ensembl:ENSG00000166347 ncbigene:1528 hgnc.symbol:CYB5A uniprot:P00167;uniprot:A0A384ME44;uniprot:J3KNC7 P450c17 Protein ensembl:ENSG00000148795 "" ensembl:ENSG00000148795 ncbigene:1586 hgnc.symbol:CYP17A1 uniprot:A0A1W2PRK7;uniprot:A0A1W2PQ28;uniprot:Q1HB44;uniprot:A0A1W2PRY0;uniprot:P05093;uniprot:A0A1W2PQT5 steroid 5 alpha-reductase 2 Protein ensembl:ENSG00000277893 "" ensembl:ENSG00000277893 ncbigene:6716 hgnc.symbol:SRD5A2 uniprot:P31213 P450Aro Protein ensembl:ENSG00000137869 "" ensembl:ENSG00000137869 ncbigene:1588 hgnc.symbol:CYP19A1 uniprot:H0YKN1;uniprot:H0YLS2;uniprot:H0YNJ7;uniprot:P11511;uniprot:H0YK57;uniprot:H0YLP1;uniprot:E9PGZ6;uniprot:E7EQ08;uniprot:E7EPL6;uniprot:A0A024R5S8 P450c11 Protein ensembl:ENSG00000160882 "" ensembl:ENSG00000160882 ncbigene:1584 hgnc.symbol:CYP11B1 uniprot:P15538;uniprot:Q4VAR0;uniprot:H0YBR4 HSD3B1 Protein ncbigene:3283 "" ensembl:ENSG00000203857 ncbigene:3283 hgnc.symbol:HSD3B1 uniprot:E9PRN7;uniprot:P14060 3B-OH-delta-Steroid Dh Protein eccode:1.1.1.145 "" Corticosterone 18-Monooxy Protein eccode:1.14.15.5 "EC number: 1.14.15.5" 3-Oxo-5b-Steroid Dh Protein uniprot:3O5B "" 3a-Hydroxy-steroid Dh Protein eccode:1.1.1.50 "SPs:DIDH RAT" 20b-Hydroxy-steroid Dh Protein eccode:1.1.1.53 "1.1.1.53, similiar SP:2BHD STREX" Cortisone beta-reductase Protein eccode:1.3.1.3 "1.3.1.3" (R)20-hydroxy-steroid Dh Protein eccode:1.1.1.53 "1.1.1.53, similiar SP:2BHD STREX"