Label Type Identifier Comment Ensembl NCBI gene HGNC UniProt Wikidata ChEBI InChI PubChem ChemSpider HMDB KEGG LipidMaps 2-Oxoadipate Metabolite chemspider:19951093 "2-Oxoadipate" wikidata:Q27124738 chebi:57499 inchikey:FGSBNBBHOZHUBO-UHFFFAOYSA-L pubchem.compound:23615192 chemspider:19951093 Anthranilate Metabolite chemspider:4573598 "Anthranilate" wikidata:Q27101976 chebi:16567 inchikey:RWZYAGGXGHYGMB-UHFFFAOYSA-M pubchem.compound:5459842 chemspider:4573598 Indole-3-acetate Metabolite chemspider:779 "AKA IAA, Indole Acetic Acid; Indole acetic acid is converted to skatole by Lactobacillus, Clostridium, Bacteroides, and others." wikidata:Q27104160 chebi:30854 inchikey:SEOVTRFCIGRIMH-UHFFFAOYSA-M pubchem.compound:801 chemspider:779 hmdb:HMDB0302181 5-hydroxykynurenamine Metabolite chebi:62214 "5-Hydroxykynurenamine" wikidata:Q27131688 chebi:62214 inchikey:JANBBPTXDKFOQR-UHFFFAOYSA-O pubchem.compound:52921618 chemspider:21232487 (S)-3-Hydroxybutyryl-CoA Metabolite kegg.compound:C01144 "(S)-3-Hydroxybutanoyl-CoA" wikidata:Q27089442 chebi:15453 inchikey:QHHKKMYHDBRONY-BEVJUKKNSA-N;inchikey:QHHKKMYHDBRONY-VKBDFPRVSA-N pubchem.compound:9543037;pubchem.compound:439419 chemspider:7822010 hmdb:HMDB0303997;hmdb:HMDB0062259 kegg.compound:C01144 lipidmaps:LMFA07050153 5-Methoxyindoleacetate Metabolite chemspider:14533147 "5-Methoxyindoleacetate" wikidata:Q42412390 inchikey:ITSUZTOXIGCANA-UHFFFAOYSA-N pubchem.compound:19821420 chemspider:14533147 2-Aminomuconate Metabolite kegg.compound:C03824 "2-Aminomuconate" wikidata:Q2823203 chebi:77634;chebi:15745 inchikey:QCGTZPZKJPTAEP-REDYYMJGSA-N pubchem.compound:5280625 chemspider:4444230 hmdb:HMDB0001280 kegg.compound:C03824 lipidmaps:LMFA01060191 3-Hydroxy-L-kynurenine Metabolite kegg.compound:C03227 "AKA 3-Hydroxy-L-kynurenine, 3H-KYN" wikidata:Q27102345 chebi:17380;chebi:58125 inchikey:VCKPUUFAIGNJHC-LURJTMIESA-N pubchem.compound:49791998;pubchem.compound:11811 chemspider:11318 hmdb:HMDB0011631 kegg.compound:C03227 N-formylanthranilate Metabolite wikidata:Q27103061 "Formylanthranilate" wikidata:Q27103061 chebi:18410 inchikey:LLLPDUXGHXIXIW-UHFFFAOYSA-M pubchem.compound:5459905 chemspider:4573637 2-Aminomuconate Metabolite kegg.compound:C02220 "2-Aminomuconate" wikidata:Q61484203 chebi:15745;chebi:189698 inchikey:ZRHONLCTYUYMIQ-HSFFGMMNSA-N pubchem.compound:5280499 chemspider:4444139 hmdb:HMDB0001241 kegg.compound:C02220 lipidmaps:LMFA01170082 4,8-Dihydroxyquinoline Metabolite chebi:28883 "4,8-Dihydroxyquinoline" wikidata:Q27103942 chebi:28883 inchikey:PYELIMVFIITPER-UHFFFAOYSA-N pubchem.compound:440737 chemspider:389608 hmdb:HMDB0060289 kegg.compound:C05637 Cinnavalininate Metabolite kegg.compound:C05640 "Cinnavalininate" wikidata:Q27106176 chebi:3715 inchikey:FSBKJYLVDRVPTK-UHFFFAOYSA-N pubchem.compound:114918 chemspider:102864 hmdb:HMDB0004078 kegg.compound:C05640 3-Hydroxykynurenamine Metabolite hmdb:HMDB0060281 "3-Hydroxykynurenamine" inchikey:ODOPEICAGBYCFH-UHFFFAOYSA-N pubchem.compound:440736 hmdb:HMDB0060281 kegg.compound:C05636 Indole-3-acetaldehyde Metabolite chemspider:778 "AKA IAAId" wikidata:Q27102813 chebi:18086 inchikey:WHOOUMGHGSPMGR-UHFFFAOYSA-N pubchem.compound:800 chemspider:778 hmdb:HMDB0001190 kegg.compound:C00637 Formyl-5-hydroxykynurenamine Metabolite hmdb:HMDB0012948 "" chebi:28736 inchikey:CKAXPTWYSHDIBN-UHFFFAOYSA-N pubchem.compound:440743 chemspider:389614 hmdb:HMDB0012948 kegg.compound:C05647 2-Amino-3-carboxymuconate Metabolite kegg.compound:C04409 "2-Amino-3-carboxymuconate" wikidata:Q2823201 chebi:995 inchikey:KACPVQQHDVBVFC-OIFXTYEKSA-N pubchem.compound:5280673 chemspider:4444266;chemspider:7822292 hmdb:HMDB0001330 kegg.compound:C04409 Serotonin Metabolite chemspider:5013 "AKA 3-(2-Aminoethyl)-1H-indol-5-ol" wikidata:Q167934 chebi:28790 inchikey:QZAYGJVTTNCVMB-UHFFFAOYSA-N pubchem.compound:5202 chemspider:5013 hmdb:HMDB0000259 kegg.compound:C00780 3-Hydroxyanthranilate Metabolite chemspider:7822291 "AKA 3-Hydroxyanthranilate, 3-HAA" wikidata:Q27104371 chebi:36559 inchikey:WJXSWCUQABXPFS-UHFFFAOYSA-M pubchem.compound:54675871 chemspider:7822291 Formyl-N-acetyl-5-methoxykynurenamine Metabolite kegg.compound:C05642 "Formyl-N-acetyl-5-methoxykynurenamine" wikidata:Q32039049 chebi:194285 inchikey:JYWNYMJKURVPFH-UHFFFAOYSA-N pubchem.compound:171161 chemspider:149637 hmdb:HMDB0004259 kegg.compound:C05642 5-Hydroxyindoleacetate Metabolite chemspider:10637170 "5-Hydroxyindoleacetate" wikidata:Q28000005 inchikey:KCWQSNFJXVMEQC-UHFFFAOYSA-N pubchem.compound:15919788 chemspider:10637170 hmdb:HMDB0257587 Quinolinate Metabolite chemspider:2777129 "" wikidata:Q27103076 chebi:19775 inchikey:LOAUVZALPPNFOQ-UHFFFAOYSA-M pubchem.compound:3538644 chemspider:2777129 Formylkynurenine Metabolite cas:1022-31-7 "Formylkynurenine" wikidata:Q71982 chebi:18377 inchikey:BYHJHXPTQMMKCA-UHFFFAOYSA-N pubchem.compound:25245041;pubchem.compound:910 chemspider:886 hmdb:HMDB0001200 kegg.compound:C02406 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate Metabolite hmdb:HMDB0004083 "" chebi:27593 inchikey:YCJNYHCCOXVYAF-UHFFFAOYSA-N pubchem.compound:440741 chemspider:389612 hmdb:HMDB0004083 kegg.compound:C05645 ILA Metabolite chebi:55528 "AKA Indole-3-lactic acid" wikidata:Q27124345 chebi:55528 inchikey:XGILAAMKEQUXLS-SNVBAGLBSA-N pubchem.compound:676158 chemspider:588901 skatole Metabolite chebi:9171 " Indole acetic acid is converted to skatole by Lactobacillus, Clostridium, Bacteroides, and others." wikidata:Q412281 chebi:9171 inchikey:ZFRKQXVRDFCRJG-UHFFFAOYSA-N pubchem.compound:6736 chemspider:6480 hmdb:HMDB0000466 kegg.compound:C08313 Indolepyruvate Metabolite kegg.compound:C00331 "AKA IPYA, IP" wikidata:Q23905803 chebi:29750 inchikey:RSTKLPZEZYGQPY-UHFFFAOYSA-N pubchem.compound:803 chemspider:781 hmdb:HMDB0060484 kegg.compound:C00331 Acetyl-CoA Metabolite cas:72-89-9 "Acetyl-CoA" wikidata:Q715317 chebi:15351 inchikey:ZSLZBFCDCINBPY-ZSJPKINUSA-N pubchem.compound:444493 chemspider:392413 hmdb:HMDB0001206 kegg.compound:C00024 lipidmaps:LMFA07050281 alpha-tocopherol Metabolite chebi:22470 "" chebi:22470 Indole Metabolite chebi:35581 "" wikidata:Q77894008 chebi:35581 5-Hydroxy-L-tryptophan Metabolite hmdb:HMDB0000472 "'The neurotransmitter 5-HT is produced in the brain through the Trp hydroxylase 2 enzyme (TpH2), [...], more than 90% of the body's 5-HT is produced in the gut and particularly in enterochromaffin cells (ECs), a specialized subtype of intestinal epithelial cell.' " chebi:17780 inchikey:LDCYZAJDBXYCGN-VIFPVBQESA-N pubchem.compound:439280 chemspider:388413 hmdb:HMDB0000472 kegg.compound:C00643 Butyrate Metabolite chebi:17968 "" wikidata:Q55582441 chebi:17968 inchikey:FERIUCNNQQJTOY-UHFFFAOYSA-M pubchem.compound:104775 chemspider:94582 L-Kynurenine Metabolite cas:343-65-7 "L-Kynurenine" wikidata:Q32908783 chebi:28683 inchikey:YGPSJZOEDVAXAB-UHFFFAOYSA-N pubchem.compound:846;pubchem.compound:25245862 hmdb:HMDB0250769 kegg.compound:C01718 Melatonin Metabolite hmdb:HMDB0001389 "" chebi:16796 inchikey:DRLFMBDRBRZALE-UHFFFAOYSA-N pubchem.compound:896 chemspider:872 hmdb:HMDB0001389 kegg.compound:C01598 5-Hydroxykynurenine Metabolite cas:484-78-6 "" wikidata:Q2815992 chebi:1547 inchikey:VCKPUUFAIGNJHC-UHFFFAOYSA-N pubchem.compound:25244175;pubchem.compound:89 chemspider:87 hmdb:HMDB0000732 kegg.compound:C02794 Xanthurenic acid Metabolite hmdb:HMDB0000881 "" chebi:10072 inchikey:FBZONXHGGPHHIY-UHFFFAOYSA-N pubchem.compound:5699 chemspider:5497 hmdb:HMDB0000881 kegg.compound:C02470 Indole-3-acetamide Metabolite chebi:16031 "AKA IAM" wikidata:Q27097844 chebi:16031 inchikey:ZOAMBXDOGPRZLP-UHFFFAOYSA-N pubchem.compound:397 chemspider:386 hmdb:HMDB0029739 kegg.compound:C02693 N-Methylserotonin Metabolite hmdb:HMDB0004369 "" chebi:48294 inchikey:ASUSBMNYRHGZIG-UHFFFAOYSA-N pubchem.compound:150885 chemspider:132989 hmdb:HMDB0004369 kegg.compound:C06212 Tryptophol Metabolite chebi:17890 "" wikidata:Q5479351 chebi:17890 inchikey:MBBOMCVGYCRMEA-UHFFFAOYSA-N pubchem.compound:10685 chemspider:10235 hmdb:HMDB0003447 kegg.compound:C00955 Tryptamine Metabolite cas:61-54-1 "" wikidata:Q409439 chebi:16765 inchikey:APJYDQYYACXCRM-UHFFFAOYSA-N pubchem.compound:1150 chemspider:1118 hmdb:HMDB0000303 kegg.compound:C00398 5-Hydroxy-N-formylkynurenine Metabolite hmdb:HMDB0004086 "" chebi:2065 inchikey:LSTOUSIIVKMJBU-UHFFFAOYSA-N pubchem.compound:440744 chemspider:389615 hmdb:HMDB0004086 kegg.compound:C05648 4,6-Dihydroxyquinoline Metabolite hmdb:HMDB0004077 "" chebi:28799 inchikey:XFALURCRIGINGT-UHFFFAOYSA-N pubchem.compound:440738 chemspider:389609 hmdb:HMDB0004077 kegg.compound:C05639 indole-sulfonic acid Metabolite pubchem.compound:12904055 "" wikidata:Q113481617 inchikey:MBGDTSHOGKMEKH-UHFFFAOYSA-N pubchem.compound:12904055 SCFAs Metabolite chebi:26666 "Short-Chain-fatty-acids" wikidata:Q2698455 chebi:26666 L-Tryptophan Metabolite cas:73-22-3 "" wikidata:Q106345470;wikidata:Q181003 chebi:57912;chebi:16828 inchikey:QIVBCDIJIAJPQS-VIFPVBQESA-N pubchem.compound:6305;pubchem.compound:6923516 chemspider:6066 hmdb:HMDB0000929 kegg.compound:C00078 Kynurenic Acid Metabolite chebi:18344 "" wikidata:Q642217 chebi:18344 inchikey:HCZHHEIFKROPDY-UHFFFAOYSA-N pubchem.compound:3845 chemspider:3712 hmdb:HMDB0000715 kegg.compound:C01717 Acetoacetyl-CoA Metabolite kegg.compound:C00332 "" wikidata:Q2639429 chebi:15345 inchikey:OJFDKHTZOUZBOS-CITAKDKDSA-N pubchem.compound:92153 chemspider:83198 hmdb:HMDB0001484 kegg.compound:C00332 lipidmaps:LMFA07050030 Indican Metabolite chebi:16700 "" wikidata:Q418392 chebi:16700 inchikey:XVARCVCWNFACQC-RKQHYHRCSA-N pubchem.compound:441564 chemspider:390239 hmdb:HMDB0061755 kegg.compound:C08481 N-Methyltryptamine Metabolite chebi:28136 "" wikidata:Q308875 chebi:28136 inchikey:NCIKQJBVUNUXLW-UHFFFAOYSA-N pubchem.compound:6088 chemspider:5863 hmdb:HMDB0004370 kegg.compound:C06213 Crotonoyl-CoA Metabolite kegg.compound:C00877 "" wikidata:Q303169 chebi:15473 inchikey:KFWWCMJSYSSPSK-PAXLJYGASA-N pubchem.compound:5497143 chemspider:4593713 hmdb:HMDB0002009 kegg.compound:C00877 lipidmaps:LMFA07050307 5-Hydroxyindoleacetaldehyde Metabolite hmdb:HMDB0004073 "AKA 5-HIAA" chebi:50157 inchikey:OBFAPCIUSYHFIE-UHFFFAOYSA-N pubchem.compound:74688 chemspider:67261 hmdb:HMDB0004073 kegg.compound:C05634 4-aminobenzoic acid Metabolite chebi:30753 "" wikidata:Q284959 chebi:30753;chebi:194474 inchikey:ALYNCZNDIQEVRV-UHFFFAOYSA-N pubchem.compound:978 chemspider:953 hmdb:HMDB0001392 kegg.compound:C00568 Indolyl acryloyl glycine Metabolite chebi:145761 "" wikidata:Q15411025 chebi:145761 inchikey:DUIFVCFSAWHIOD-AATRIKPKSA-N pubchem.compound:5370648 chemspider:4521424 hmdb:HMDB0006005 Tyramine Metabolite chebi:15760 "" wikidata:Q165930 chebi:15760 inchikey:DZGWFCGJZKJUFP-UHFFFAOYSA-N pubchem.compound:5610 chemspider:5408 hmdb:HMDB0000306 kegg.compound:C00483 6-Hydroxymelatonin Metabolite cas:2208-41-5 "" wikidata:Q20707319 chebi:2198 inchikey:OMYMRCXOJJZYKE-UHFFFAOYSA-N pubchem.compound:1864 chemspider:1794 hmdb:HMDB0004081 kegg.compound:C05643 Indole-3-aldehyde Metabolite chebi:28238 "AKA IAId" wikidata:Q27103575 chebi:28238 inchikey:OLNJUISKUQQNIM-UHFFFAOYSA-N pubchem.compound:10256 chemspider:9838 hmdb:HMDB0029737 kegg.compound:C08493 Glutaryl-CoA Metabolite kegg.compound:C00527 "" wikidata:Q3066713 chebi:15524 inchikey:SYKWLIJQEHRDNH-CKRMAKSASA-N pubchem.compound:3081383 chemspider:2338999 hmdb:HMDB0001339 kegg.compound:C00527 lipidmaps:LMFA07050324 cholate Metabolite chebi:29747 "" wikidata:Q27104085 chebi:29747 inchikey:BHQCQFFYRZLCQQ-OELDTZBJSA-M pubchem.compound:5460314 chemspider:4573890 N-Acetylserotonin Metabolite cas:1210-83-9 "AKA N-Acetylserotonin, NAS" wikidata:Q4847704 chebi:17697 inchikey:MVAWJSIDNICKHF-UHFFFAOYSA-N pubchem.compound:903 chemspider:879 hmdb:HMDB0001238 kegg.compound:C00978 picolinate Metabolite kegg.compound:C10164 "" wikidata:Q416682 chebi:28747 inchikey:SIOXPEMLGUPBBT-UHFFFAOYSA-N pubchem.compound:1018 chemspider:993 hmdb:HMDB0002243 kegg.compound:C10164 IA Metabolite chebi:132244 "AKA Indole acrylic acid" wikidata:Q27225487 chebi:132244 inchikey:PLVPPLCLBIEYEA-AATRIKPKSA-N pubchem.compound:5375048 chemspider:4524636 hmdb:HMDB0000734 IPA Metabolite chebi:43580 "AKA Indole-3-propionic acid" wikidata:Q21098993 chebi:43580 inchikey:GOLXRNDWAUTYKT-UHFFFAOYSA-N pubchem.compound:3744 chemspider:3613 hmdb:HMDB0002302 Quinaldic Acid Metabolite chebi:18386 "" wikidata:Q17189267 chebi:18386 inchikey:LOAUVZALPPNFOQ-UHFFFAOYSA-N pubchem.compound:7124 chemspider:6857 hmdb:HMDB0000842 kegg.compound:C06325 Indole acetic glutamine Metabolite chebi:176458 "" chebi:176458 IDO2 GeneProduct ncbigene:169355 "" ensembl:ENSG00000188676 ncbigene:169355 hgnc.symbol:IDO2 uniprot:Q6ZQW0 GCDH GeneProduct ncbigene:2639 "predicted" ensembl:ENSG00000105607 ncbigene:2639 hgnc.symbol:GCDH uniprot:K7ES74;uniprot:K7EQ99;uniprot:K7ER63;uniprot:K7EKT3;uniprot:K7ERX1;uniprot:Q92947;uniprot:K7ESA6;uniprot:A0A024R7F9;uniprot:K7EKH1 ALDH2 GeneProduct ncbigene:217 "" ensembl:ENSG00000111275 ncbigene:217 hgnc.symbol:ALDH2 uniprot:A0A384NPN7;uniprot:P05091;uniprot:S4R3S4;uniprot:F8VSB0 4.1.1.- GeneProduct eccode:4.1.1.- "Unclear which specific protein acts in this reaction" ASMT GeneProduct ncbigene:438 "" ensembl:ENSG00000292336;ensembl:ENSG00000196433 ncbigene:438 hgnc.symbol:ASMT uniprot:X5D784;uniprot:I7HFW6;uniprot:X5D2A4;uniprot:A0A024RBT9;uniprot:P46597 IDO2 GeneProduct ensembl:ENSG00000188676 "" ensembl:ENSG00000188676 ncbigene:169355 hgnc.symbol:IDO2 uniprot:Q6ZQW0 1.5.1.- GeneProduct eccode:1.5.1.- "Unclear which specific protein acts in this reaction." CYP1A1 GeneProduct ncbigene:1543 "" ensembl:ENSG00000140465 ncbigene:1543 hgnc.symbol:CYP1A1 uniprot:E7EMT5;uniprot:P04798;uniprot:A0N0X8;uniprot:A4F3V8 DLD GeneProduct ncbigene:1738 "aka OADH" ensembl:ENSG00000091140 ncbigene:1738 hgnc.symbol:DLD uniprot:F2Z2E3;uniprot:F8WDM5;uniprot:F8WDY5;uniprot:P09622;uniprot:E9PEX6;uniprot:A0A024R713 MAOA GeneProduct ncbigene:4128 "" ensembl:ENSG00000189221 ncbigene:4128 hgnc.symbol:MAOA uniprot:A0A8I5KP93;uniprot:Q53YE7;uniprot:A0A8I5KUC3;uniprot:P21397 DDC GeneProduct ncbigene:1644 "In Agus et al, this protein is called 'AAAD', aka 'aromatic amino acid decarboxylase', which is known in UniProt at DCC; AAAD is an unrelated protein and its addition to Figure 2 of this paper is questionable [PMID:29902437]. Fig. 1 [PMID:31825083] mentions AADC, in peripheral synthesis." ensembl:ENSG00000132437 ncbigene:1644 hgnc.symbol:DDC uniprot:H7BZF7;uniprot:A0A0S2Z3N4;uniprot:C9JMP0;uniprot:P20711;uniprot:F8WER1;uniprot:A0A087WU57;uniprot:A0A087WV24 CAT GeneProduct ncbigene:847 "" ensembl:ENSG00000121691 ncbigene:847 hgnc.symbol:CAT uniprot:A0A3B3ITJ0;uniprot:P04040;uniprot:A0A384P5Q0 STAT1 GeneProduct ensembl:ENSG00000115415 "" ensembl:ENSG00000115415 ncbigene:6772 hgnc.symbol:STAT1 uniprot:E9PH66;uniprot:A0A669KBK4;uniprot:A0A8V8TMY9;uniprot:E7EPD2;uniprot:J3KPM9;uniprot:Q67C41;uniprot:A0A669KB17;uniprot:A0A8V8TN81;uniprot:A0A669KB56;uniprot:A0A669KB68;uniprot:A0A669KB52;uniprot:A0A669KB53;uniprot:A0A669KB75;uniprot:D2KFR9;uniprot:P42224;uniprot:A0A669KBA4;uniprot:E7ENM1;uniprot:A0A669KBI6;uniprot:A0A8V8TLI6 DDC GeneProduct ncbigene:1644 "" ensembl:ENSG00000132437 ncbigene:1644 hgnc.symbol:DDC uniprot:H7BZF7;uniprot:A0A0S2Z3N4;uniprot:C9JMP0;uniprot:P20711;uniprot:F8WER1;uniprot:A0A087WU57;uniprot:A0A087WV24 DDC GeneProduct ncbigene:1644 "Known under two EC numbers: aromatic-L-amino-acid/L-tryptophan decarboxylase [EC:4.1.1.28; EC:4.1.1.105]" ensembl:ENSG00000132437 ncbigene:1644 hgnc.symbol:DDC uniprot:H7BZF7;uniprot:A0A0S2Z3N4;uniprot:C9JMP0;uniprot:P20711;uniprot:F8WER1;uniprot:A0A087WU57;uniprot:A0A087WV24 ACAT1 GeneProduct ncbigene:38 "" ensembl:ENSG00000075239 ncbigene:38 hgnc.symbol:ACAT1 uniprot:E9PRQ6;uniprot:A0A5F9ZHD4;uniprot:A0A5F9ZHJ7;uniprot:H0YEL7;uniprot:A0A140VJX1;uniprot:A0A5F9ZHH9;uniprot:A0A5F9ZI66;uniprot:A0A5F9ZHL1;uniprot:A0A5F9ZHJ0;uniprot:A0A5F9ZHL7;uniprot:P24752 INDO2 GeneProduct ncbigene:3620 "" ensembl:ENSG00000131203 ncbigene:3620 hgnc.symbol:IDO1 uniprot:A0A348GSI3;uniprot:E5RIX2;uniprot:J3KN03;uniprot:P14902;uniprot:A0A140T9Z2;uniprot:E5RH36 AFMID GeneProduct ncbigene:125061 "" ensembl:ENSG00000183077 ncbigene:125061 hgnc.symbol:AFMID uniprot:Q63HM1;uniprot:W4VSQ7;uniprot:K7ELV9;uniprot:K7EQK5;uniprot:K7EMI4;uniprot:K7EMM5;uniprot:K7EPF8;uniprot:K7EIX3;uniprot:K7EK09 AANAT GeneProduct ncbigene:15 "" ensembl:ENSG00000129673 ncbigene:15 hgnc.symbol:AANAT uniprot:Q16613;uniprot:F1T0I5;uniprot:K7ERF6;uniprot:K7ESH7 ALDH8A1 GeneProduct ncbigene:64577 "" ensembl:ENSG00000118514 ncbigene:64577 hgnc.symbol:ALDH8A1 uniprot:Q9H2A2;uniprot:E9PKV1;uniprot:H0YF40 AOX1 GeneProduct ncbigene:316 "" ensembl:ENSG00000138356 ncbigene:316 hgnc.symbol:AOX1 uniprot:C9J244;uniprot:Q06278;uniprot:H7BXF7;uniprot:H7C3Q1 AADAT GeneProduct ncbigene:56267 "" ensembl:ENSG00000137944 ncbigene:56267 hgnc.symbol:KYAT3 uniprot:Q6YP21;uniprot:B4DW13;uniprot:A0A0A0MRN7 ACMSD GeneProduct ncbigene:130013 "" ensembl:ENSG00000153086 ncbigene:130013 hgnc.symbol:ACMSD uniprot:Q8TDX5;uniprot:A0A0S2Z681 KMO GeneProduct ncbigene:8564 "liver PW" ensembl:ENSG00000117009 ncbigene:8564 hgnc.symbol:KMO uniprot:H0Y320;uniprot:O15229 KYNU GeneProduct ncbigene:8942 "AKA kynureninase" ensembl:ENSG00000115919 ncbigene:8942 hgnc.symbol:KYNU uniprot:A0A087WYM2;uniprot:F8WEP1;uniprot:B8ZZA3;uniprot:A0A087WYQ7;uniprot:A0A087X297;uniprot:Q16719 INMT GeneProduct ncbigene:11185 "" ensembl:ENSG00000241644 ncbigene:11185 hgnc.symbol:INMT uniprot:O95050 HAAO GeneProduct ncbigene:23498 "AKA 3-hydroxyanthraniate 3,4-dioxygenase" ensembl:ENSG00000162882 ncbigene:23498 hgnc.symbol:HAAO uniprot:C9IY88;uniprot:P46952 AOC1 GeneProduct ncbigene:26 "aka ABP1" ensembl:ENSG00000002726 ncbigene:26 hgnc.symbol:AOC1 uniprot:C9J0G8;uniprot:P19801;uniprot:C9J2J4 MAOA GeneProduct ncbigene:4128 "AKA Monoamine Ozydase (MAO)" ensembl:ENSG00000189221 ncbigene:4128 hgnc.symbol:MAOA uniprot:A0A8I5KP93;uniprot:Q53YE7;uniprot:A0A8I5KUC3;uniprot:P21397 IDO1 GeneProduct ensembl:ENSG00000131203 "" ensembl:ENSG00000131203 ncbigene:3620 hgnc.symbol:IDO1 uniprot:A0A348GSI3;uniprot:E5RIX2;uniprot:J3KN03;uniprot:P14902;uniprot:A0A140T9Z2;uniprot:E5RH36 KYNU GeneProduct ncbigene:8942 "" ensembl:ENSG00000115919 ncbigene:8942 hgnc.symbol:KYNU uniprot:A0A087WYM2;uniprot:F8WEP1;uniprot:B8ZZA3;uniprot:A0A087WYQ7;uniprot:A0A087X297;uniprot:Q16719 ECHS1 GeneProduct ncbigene:1892 "" ensembl:ENSG00000127884 ncbigene:1892 hgnc.symbol:ECHS1 uniprot:P30084 TDO2 GeneProduct ncbigene:6999 "liver PW" ensembl:ENSG00000151790 ncbigene:6999 hgnc.symbol:TDO2 uniprot:D6RA50;uniprot:D6RB68;uniprot:P48775 TPH2 GeneProduct ncbigene:121278 "produced in the brain; central synthesis" ensembl:ENSG00000139287 ncbigene:121278 hgnc.symbol:TPH2 uniprot:Q8IWU9 IDO2 GeneProduct ncbigene:169355 "brain, liver and gut PW" ensembl:ENSG00000188676 ncbigene:169355 hgnc.symbol:IDO2 uniprot:Q6ZQW0 ALDH2 Protein uniprot:P05091 "" ensembl:ENSG00000111275 ncbigene:217 hgnc.symbol:ALDH2 uniprot:A0A384NPN7;uniprot:P05091;uniprot:S4R3S4;uniprot:F8VSB0 IDO1 Protein uniprot:P14902 "AKA indoleamine 2,3-dioxygenase, in both immune and epithelial cells [PMID: 22688187]" ensembl:ENSG00000131203 ncbigene:3620 hgnc.symbol:IDO1 uniprot:A0A348GSI3;uniprot:E5RIX2;uniprot:J3KN03;uniprot:P14902;uniprot:A0A140T9Z2;uniprot:E5RH36 TpH1 Protein uniprot:P17752 "AKA Trp hydroxylase 1, produced in intestinal epithelial cells; peripheral synthesis" ensembl:ENSG00000129167 ncbigene:7166 hgnc.symbol:TPH1 uniprot:E9PR49;uniprot:E7EMX4;uniprot:P17752 HDAC Protein interpro:IPR000286 "Family of proteins" MAOA Protein ncbigene:4128 "" ensembl:ENSG00000189221 ncbigene:4128 hgnc.symbol:MAOA uniprot:A0A8I5KP93;uniprot:Q53YE7;uniprot:A0A8I5KUC3;uniprot:P21397 AHR Protein hgnc.symbol:AHR "" ensembl:ENSG00000106546 ncbigene:196 hgnc.symbol:AHR uniprot:A0A2R8Y7G1;uniprot:P35869;uniprot:A0A024R9Z8 IL4I1 Protein uniprot:Q96RQ9 "" ensembl:ENSG00000104951 ncbigene:259307 hgnc.symbol:IL4I1 uniprot:Q96RQ9;uniprot:M0R1L1;uniprot:M0QXY7;uniprot:M0QYH9;uniprot:M0QYW8;uniprot:M0R2S9 fldH Protein uniprot:G9EZR6 "AKA phenyllactate dehydrogenase or indolelactic acid dehydrogenase (ILDH); species: Clostridium sporogenes (strain ATCC 7955 / DSM 767 / NBRC 16411 / NCIMB 8053 / NCTC 8594 / PA 3679)" ArAT Protein eccode:2.6.1.57 "AKA Aromatic amino acid aminotransferase, group of proteins" KYAT1 Protein uniprot:Q16773 "KAT I/glutamine transaminase K/cysteine conjugate beta-lyase 1" ensembl:ENSG00000171097 ncbigene:883 hgnc.symbol:KYAT1 uniprot:A8K563;uniprot:Q16773;uniprot:Q5T277;uniprot:Q5T276;uniprot:B7Z4W5;uniprot:Q5T278 TMO Protein uniprot:P48775 "AKA Tryptophan 2,3-dioxygenase; abbreviation TMO is not know in UniProt (TDO2 is the gene name)." ensembl:ENSG00000151790 ncbigene:6999 hgnc.symbol:TDO2 uniprot:D6RA50;uniprot:D6RB68;uniprot:P48775 TNA Protein uniprot:P31015 "AKA Tryptophanase (2); Species: Symbiobacterium thermophilum (strain T / IAM 14863)" HADH Protein uniprot:Q16836 "" ensembl:ENSG00000138796 ncbigene:3033 hgnc.symbol:HADH uniprot:A0A1W2PP40;uniprot:A0A0D9SFP2;uniprot:Q16836;uniprot:A0A804HJW7;uniprot:A0A804HKJ2;uniprot:A0A0A0MSE2;uniprot:E9PF18;uniprot:A0A804HJK7;uniprot:A0A1W2PQC2;uniprot:A0A1W2PRM6;uniprot:J3KR89;uniprot:A0A140VK76;uniprot:A0A1W2PQV5;uniprot:A0A1W2PRT2;uniprot:A0A804HLB5;uniprot:A0A1W2PNM1;uniprot:A0A1W2PQ78;uniprot:A0A1W2PQ55 porB Protein uniprot:Q9ZKA3 "AKA pyruvate : ferrodoxin oxidoreductase B; Species: Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99)" acdA Protein uniprot:P45867 "AKA acyl-CoA dehydrogenase; Species: Bacillus subtilis (strain 168)" fldH Protein uniprot:J7SHB8 "AKA phenyllactate dehydrogenase or indolelactic acid dehydrogenase (ILDH); species: Clostridium sporogenes (strain ATCC 15579)" fldB Protein uniprot:Q93AL9 "AKA phenyllactate dehydratase; fldBC is know as two entries in UniProt (fldB and fldC); Species: Clostridium sporogenes" fldC Protein uniprot:Q93AL8 "AKA phenyllactate dehydratase; fldBC is know as two entries in UniProt (fldB and fldC); Species: Clostridium sporogenes" acdA Protein uniprot:J7TF92 "AKA acyl-CoA dehydrogenase; Species: Clostridium sporogenes (strain ATCC 15579)" TNA Protein uniprot:P31014 "AKA Tryptophanase (1); Species: Symbiobacterium thermophilum (strain T / IAM 14863)" TNA Protein uniprot:Q9ZNA8 "AKA Tryptophanase; Species: Proteus inconstans" TNA Protein uniprot:O07674 "AKA Tryptophanase; Species: Haemophilus influenzae" KYAT2 Protein uniprot:Q8N5Z0 "KAT II/aminoadipate aminotransferase" ensembl:ENSG00000109576 ncbigene:51166 hgnc.symbol:AADAT uniprot:D6REB9;uniprot:Q8N5Z0;uniprot:D6RC56;uniprot:D6RFY7;uniprot:Q4W5N8 KYAT3 Protein uniprot:Q6YP21 "KAT III/cysteine conjugate beta-lyase 2" ensembl:ENSG00000137944 ncbigene:56267 hgnc.symbol:KYAT3 uniprot:Q6YP21;uniprot:B4DW13;uniprot:A0A0A0MRN7 KYAT4 Protein uniprot:P00505 "KAT IV/glutamic-oxaloacetic transaminase 2/mitochondrial aspartate aminotransferase" ensembl:ENSG00000125166 ncbigene:2806 hgnc.symbol:GOT2 uniprot:H3BRE7;uniprot:P00505 IDO2 Protein uniprot:Q6ZQW0 "brain, liver and gut PW" ensembl:ENSG00000188676 ncbigene:169355 hgnc.symbol:IDO2 uniprot:Q6ZQW0 STAT1 Protein uniprot:P42224 "" ensembl:ENSG00000115415 ncbigene:6772 hgnc.symbol:STAT1 uniprot:E9PH66;uniprot:A0A669KBK4;uniprot:A0A8V8TMY9;uniprot:E7EPD2;uniprot:J3KPM9;uniprot:Q67C41;uniprot:A0A669KB17;uniprot:A0A8V8TN81;uniprot:A0A669KB56;uniprot:A0A669KB68;uniprot:A0A669KB52;uniprot:A0A669KB53;uniprot:A0A669KB75;uniprot:D2KFR9;uniprot:P42224;uniprot:A0A669KBA4;uniprot:E7ENM1;uniprot:A0A669KBI6;uniprot:A0A8V8TLI6 STAT1 Protein uniprot:P42224 "FN-gamma–dependent phosphorylation of STAT1" ensembl:ENSG00000115415 ncbigene:6772 hgnc.symbol:STAT1 uniprot:E9PH66;uniprot:A0A669KBK4;uniprot:A0A8V8TMY9;uniprot:E7EPD2;uniprot:J3KPM9;uniprot:Q67C41;uniprot:A0A669KB17;uniprot:A0A8V8TN81;uniprot:A0A669KB56;uniprot:A0A669KB68;uniprot:A0A669KB52;uniprot:A0A669KB53;uniprot:A0A669KB75;uniprot:D2KFR9;uniprot:P42224;uniprot:A0A669KBA4;uniprot:E7ENM1;uniprot:A0A669KBI6;uniprot:A0A8V8TLI6