Label	Type	Identifier	Comment	Ensembl	NCBI gene	HGNC	UniProt	Wikidata	ChEBI	InChI
7-Dehydrocholesterol	Metabolite	inchikey:UCTLRSWJYQTBFZ-DDPQNLDTSA-N	aka 7-DHC</br>abundant in SLOS.					wikidata:Q139350	chebi:17759;chebi:17759	inchikey:UCTLRSWJYQTBFZ-DDPQNLDTSA-N
3b,5a,6b-Trihydroxycholan-24-oyl-glycine	Metabolite	inchikey:PVXZQUUYXFMXMF-ABSIFXOISA-N								
3b,7b-Dihydroxychol-5-en-24-oic acid	Metabolite	inchikey:PXHCARRJGFGPAC-SZQOYVLDSA-N								
Cholesterol	Metabolite	inchikey:HVYWMOMLDIMFJA-DPAQBDIFSA-N						wikidata:Q43656	chebi:16113;chebi:16113	inchikey:HVYWMOMLDIMFJA-DPAQBDIFSA-N
7b-Hydroxycholesterol	Metabolite	inchikey:OYXZMSRRJOYLLO-KGZHIOMZSA-N						wikidata:Q27074031	chebi:42989;chebi:42989	inchikey:OYXZMSRRJOYLLO-KGZHIOMZSA-N
(25R)26-Hydroxy-7-oxocholesterol	Metabolite	inchikey:LFNAJBFFWWMSEW-HNFKANRHSA-N						wikidata:Q27159806	chebi:87653;chebi:87653	inchikey:LFNAJBFFWWMSEW-HNFKANRHSA-N
Dendrogenin A	Metabolite	inchikey:AVFNYTPENXWWCA-BULFVYHESA-N						wikidata:Q61983671		inchikey:AVFNYTPENXWWCA-BULFVYHESA-N
Cholestane-3b,5a,6b,(25R)26-tetrol	Metabolite	inchikey:PFYSRSDOSXYIFG-JKYVJSSTSA-N								
3b,5a,6b-Trihydroxycholestan-(25R)26-oic acid	Metabolite	inchikey:LMWUOMGULHFSQR-HDEGCWFHSA-N								
3b-Hydroxy-7-oxochol-5-en-24-oyl-CoA	Metabolite	inchikey:HEPNPBUPTRNGJT-ILFWFKRZSA-N								
Cholestane-3b,5a,6b-triol	Metabolite	inchikey:YMMFNKXZULYSOQ-RUXQDQFYSA-N						wikidata:Q27103493	chebi:28082;chebi:73006;chebi:28082;chebi:73006	inchikey:YMMFNKXZULYSOQ-RUXQDQFYSA-N
7-Oxocholesterol	Metabolite	inchikey:YIKKMWSQVKJCOP-ABXCMAEBSA-N	aka 7-OC</br>Elevated levels found in Wolman's disease					wikidata:Q27133201	chebi:64294;chebi:64294	inchikey:YIKKMWSQVKJCOP-ABXCMAEBSA-N
3b,7b-Dihydroxychol-5-en-24-oyl-glycine	Metabolite	inchikey:BMRAURDLHOPSBE-FRMRTHFDSA-N								
7b-Peroxycholesterol	Metabolite	inchikey:KJIGLXGIVLBXCF-UOQFGJKXSA-N								
3b-Hydroxy-7-oxocholest-5-en-(25R)26-oic acid	Metabolite	inchikey:QOEPZHFZXUROGV-BXDHRDAUSA-N						wikidata:Q27159930	chebi:87783;chebi:87783	inchikey:QOEPZHFZXUROGV-BXDHRDAUSA-N
3b-Hydroxy-7-oxochol-5-en-24-oic acid	Metabolite	inchikey:JHFXTNJNQOZGEJ-HICUSVRDSA-N						wikidata:Q76294977		inchikey:JHFXTNJNQOZGEJ-HICUSVRDSA-N
3b,5a,6b-Trihydroxycholan-24-oic acid	Metabolite	inchikey:NMKAZCXSXYNCFW-DWQVTILUSA-N						wikidata:Q76294832		inchikey:NMKAZCXSXYNCFW-DWQVTILUSA-N
3b-Hydroxy-7-oxochol-5-en-24-oyl-glycine	Metabolite	inchikey:AXBXXYALPXTOOI-UBKHJBOVSA-N								
3b,5a-DiH-cholestan-6-one	Metabolite	inchikey:SJZZRXMQSAXCFD-FRAMIZMOSA-N	aka 3b,5a-Dihydroxycholestan-6-one							
3b,7b-Dihydroxycholest-5-en-(25R)26-oic acid	Metabolite	inchikey:GYJSAWZGYQXRBS-WMYDBBFWSA-N								
3b,5a,6b-Trihydroxycholan-24-oyl-CoA	Metabolite	inchikey:WRWBXZATSFAUGF-UJKOPXFNSA-N								
3b,7b-Dihydroxychol-5-en-24-oyl-CoA	Metabolite	inchikey:XRRIYAPQOCXHCP-NRNJIOKESA-N								
3b,24R-Dihydroxy-7-oxocholest-5-en-(25R)26-oyl-CoA	Metabolite	inchikey:UOHZUNSDJHLARD-JLLVOJIKSA-N								
3b,5a,6b,24R-Tetrahydroxycholestan-(25R)26-oyl-CoA	Metabolite	inchikey:PJJHUKDTGITXML-MFOUGJSISA-N								
5,6-Epoxycholesterol	Metabolite	inchikey:PRYIJAGAEJZDBO-XXGHXXDPSA-N								
7b,(25R)26-Dihydroxycholesterol	Metabolite	inchikey:RXMHNAKZMGJANZ-BMOLSTJGSA-N						wikidata:Q27074030		inchikey:RXMHNAKZMGJANZ-BMOLSTJGSA-N
3b,7b,24R-Trihydroxycholest-5-en-(25R)26-oyl-CoA	Metabolite	inchikey:BZALPCSTIFZGTP-YBYDULIXSA-N								
Cholesterol	Metabolite	inchikey:HVYWMOMLDIMFJA-DPAQBDIFSA-N						wikidata:Q43656	chebi:16113;chebi:16113	inchikey:HVYWMOMLDIMFJA-DPAQBDIFSA-N
Cholesterol	Metabolite	inchikey:HVYWMOMLDIMFJA-DPAQBDIFSA-N						wikidata:Q43656	chebi:16113;chebi:16113	inchikey:HVYWMOMLDIMFJA-DPAQBDIFSA-N
CYP7A1	GeneProduct	hgnc.symbol:CYP7A1		ensembl:ENSG00000167910	ncbigene:1581	hgnc.symbol:CYP7A1	uniprot:P22680			
NPC1	GeneProduct	hgnc.symbol:NPC1		ensembl:ENSG00000141458	ncbigene:4864	hgnc.symbol:NPC1	uniprot:K7ERW2;uniprot:K7ERM4;uniprot:O15118;uniprot:K7EIH7;uniprot:K7ENZ0;uniprot:K7EQ23			
HSD11B1	GeneProduct	hgnc.symbol:HSD11B1		ensembl:ENSG00000117594	ncbigene:3290	hgnc.symbol:HSD11B1	uniprot:P28845;uniprot:X5D2L1;uniprot:A0A087WU76;uniprot:A0A0A0MQV1			
HSD11B2	GeneProduct	hgnc.symbol:HSD11B2		ensembl:ENSG00000176387	ncbigene:3291	hgnc.symbol:HSD11B2	uniprot:R4GN04;uniprot:P80365			
CYP27A1	GeneProduct	hgnc.symbol:CYP27A1		ensembl:ENSG00000135929	ncbigene:1593	hgnc.symbol:CYP27A1	uniprot:Q02318;uniprot:F8WD90;uniprot:C9J1K5			
BACS (SLC27A5)	GeneProduct	hgnc.symbol:SLC27A5	Bile Acid CoA ligase (or synthetase)</br>microsomal protein mostly expressed in liver [PMID:24309898, 25409824(mouse)]	ensembl:ENSG00000083807	ncbigene:10998	hgnc.symbol:SLC27A5	uniprot:Q9Y2P5;uniprot:M0R075			
VLCS (SLC27A2)	GeneProduct	hgnc.symbol:SLC27A2	very-long chain acyl-CoA synthetase</br>expressed mostly in liver and kidney, and present in ER and peroxisome [PMID:24309898, 25409824(mouse)]	ensembl:ENSG00000140284	ncbigene:11001	hgnc.symbol:SLC27A2	uniprot:O14975;uniprot:G3V1R7			
AMACR	GeneProduct	hgnc.symbol:AMACR	alpha-methylacyl-CoA racemase</br>broadly expressed [PMID:24309898, 25409824(mouse)]	ensembl:ENSG00000242110	ncbigene:23600	hgnc.symbol:AMACR	uniprot:V9GYP4;uniprot:V9GYU9;uniprot:D6RB81;uniprot:Q9UHK6;uniprot:V9GZ45			
ACOX2	GeneProduct	hgnc.symbol:ACOX2		ensembl:ENSG00000168306	ncbigene:8309	hgnc.symbol:ACOX2	uniprot:C9JY29;uniprot:H7C4Q2;uniprot:C9J0G0;uniprot:H7C573;uniprot:Q99424;uniprot:H7C4Y2			
DBP	GeneProduct	hgnc.symbol:DBP	D-biofinctional protein; aka MFE2, HSD17B4	ensembl:ENSG00000105516	ncbigene:1628	hgnc.symbol:DBP	uniprot:Q10586;uniprot:M0QXW3;uniprot:M0QXP1			
SCPx (SCP2)	GeneProduct	hgnc.symbol:SCP2		ensembl:ENSG00000116171	ncbigene:6342	hgnc.symbol:SCP2	uniprot:A0A384NY87;uniprot:H0YCB0;uniprot:H0YF61;uniprot:H0YD06;uniprot:E9PLD1;uniprot:P22307;uniprot:H0YEU8			
DBP	GeneProduct	hgnc.symbol:DBP	D-biofinctional protein; aka MFE2, HSD17B4	ensembl:ENSG00000105516	ncbigene:1628	hgnc.symbol:DBP	uniprot:Q10586;uniprot:M0QXW3;uniprot:M0QXP1			
BAAT	GeneProduct	hgnc.symbol:BAAT	amino acid N-acyl transferase	ensembl:ENSG00000136881	ncbigene:570	hgnc.symbol:BAAT	uniprot:A0A6Q8PF60;uniprot:A0A6Q8PHR9;uniprot:Q14032			
CYP27A1	GeneProduct	hgnc.symbol:CYP27A1		ensembl:ENSG00000135929	ncbigene:1593	hgnc.symbol:CYP27A1	uniprot:Q02318;uniprot:F8WD90;uniprot:C9J1K5			
BACS (SLC27A5)	GeneProduct	hgnc.symbol:SLC27A5	Bile Acid CoA ligase (or synthetase)</br>microsomal protein mostly expressed in liver [PMID:24309898, 25409824(mouse)]	ensembl:ENSG00000083807	ncbigene:10998	hgnc.symbol:SLC27A5	uniprot:Q9Y2P5;uniprot:M0R075			
VLCS (SLC27A2)	GeneProduct	hgnc.symbol:SLC27A2	very-long chain acyl-CoA synthetase</br>expressed mostly in liver and kidney, and present in ER and peroxisome [PMID:24309898, 25409824(mouse)]	ensembl:ENSG00000140284	ncbigene:11001	hgnc.symbol:SLC27A2	uniprot:O14975;uniprot:G3V1R7			
AMACR	GeneProduct	hgnc.symbol:AMACR	alpha-methylacyl-CoA racemase</br>broadly expressed [PMID:24309898, 25409824(mouse)]	ensembl:ENSG00000242110	ncbigene:23600	hgnc.symbol:AMACR	uniprot:V9GYP4;uniprot:V9GYU9;uniprot:D6RB81;uniprot:Q9UHK6;uniprot:V9GZ45			
ACOX2	GeneProduct	hgnc.symbol:ACOX2		ensembl:ENSG00000168306	ncbigene:8309	hgnc.symbol:ACOX2	uniprot:C9JY29;uniprot:H7C4Q2;uniprot:C9J0G0;uniprot:H7C573;uniprot:Q99424;uniprot:H7C4Y2			
DBP	GeneProduct	hgnc.symbol:DBP	D-biofinctional protein; aka MFE2, HSD17B4	ensembl:ENSG00000105516	ncbigene:1628	hgnc.symbol:DBP	uniprot:Q10586;uniprot:M0QXW3;uniprot:M0QXP1			
SCPx (SCP2)	GeneProduct	hgnc.symbol:SCP2		ensembl:ENSG00000116171	ncbigene:6342	hgnc.symbol:SCP2	uniprot:A0A384NY87;uniprot:H0YCB0;uniprot:H0YF61;uniprot:H0YD06;uniprot:E9PLD1;uniprot:P22307;uniprot:H0YEU8			
DBP	GeneProduct	hgnc.symbol:DBP	D-biofinctional protein; aka MFE2, HSD17B4	ensembl:ENSG00000105516	ncbigene:1628	hgnc.symbol:DBP	uniprot:Q10586;uniprot:M0QXW3;uniprot:M0QXP1			
BAAT	GeneProduct	hgnc.symbol:BAAT	amino acid N-acyl transferase	ensembl:ENSG00000136881	ncbigene:570	hgnc.symbol:BAAT	uniprot:A0A6Q8PF60;uniprot:A0A6Q8PHR9;uniprot:Q14032			
HSD11B2	GeneProduct	hgnc.symbol:HSD11B2		ensembl:ENSG00000176387	ncbigene:3291	hgnc.symbol:HSD11B2	uniprot:R4GN04;uniprot:P80365			
HSD11B1	GeneProduct	hgnc.symbol:HSD11B1		ensembl:ENSG00000117594	ncbigene:3290	hgnc.symbol:HSD11B1	uniprot:P28845;uniprot:X5D2L1;uniprot:A0A087WU76;uniprot:A0A0A0MQV1			
HSD11B2	GeneProduct	hgnc.symbol:HSD11B2		ensembl:ENSG00000176387	ncbigene:3291	hgnc.symbol:HSD11B2	uniprot:R4GN04;uniprot:P80365			
HSD11B1	GeneProduct	hgnc.symbol:HSD11B1		ensembl:ENSG00000117594	ncbigene:3290	hgnc.symbol:HSD11B1	uniprot:P28845;uniprot:X5D2L1;uniprot:A0A087WU76;uniprot:A0A0A0MQV1			
HSD11B2	GeneProduct	hgnc.symbol:HSD11B2		ensembl:ENSG00000176387	ncbigene:3291	hgnc.symbol:HSD11B2	uniprot:R4GN04;uniprot:P80365			
NPC2	GeneProduct	hgnc.symbol:NPC2		ensembl:ENSG00000119655	ncbigene:10577	hgnc.symbol:NPC2	uniprot:E7EMS2;uniprot:H0YIZ1;uniprot:G3V3D1;uniprot:P61916;uniprot:A0A024R6C0;uniprot:G3V2V8;uniprot:H0YJE2;uniprot:G3V3E8;uniprot:J3KMY5			
ACOT1	Protein	uniprot:Q86TX2		ensembl:ENSG00000184227	ncbigene:641371	hgnc.symbol:ACOT1	uniprot:G3V4F2;uniprot:Q86TX2;uniprot:E9KL42			
ACOT	Protein	eccode:3.1.2.2	acyl-CoA thioesterase are a group of enzymes							
ACOT2	Protein	uniprot:P49753	'originally thought to be in peroxisome [PMID:10944470)], later found to be mitochondrial [PMID:16940157]' [https://www.uniprot.org/uniprot/P49753]	ensembl:ENSG00000119673	ncbigene:10965	hgnc.symbol:ACOT2	uniprot:P49753;uniprot:F6VI00;uniprot:A0A087WT95			
ACOT4	Protein	uniprot:Q8N9L9	'Compared to mouse peroxisomal succinyl-coenzyme A thioesterase/ACOT4, the human enzyme has a broad substrate specificity overlapping the activity of three mouse acyl-coenzyme A thioesterases, providing an explanation for the unexpectedly low number of acyl-coenzyme A thioesterase genes in the human genome [PMID:16940157]' [https://www.uniprot.org/uniprot/Q8N9L9]	ensembl:ENSG00000177465	ncbigene:122970	hgnc.symbol:ACOT4	uniprot:Q8N9L9			
ACOT6	Protein	uniprot:Q3I5F7		ensembl:ENSG00000205669	ncbigene:641372	hgnc.symbol:ACOT6	uniprot:Q3I5F7;uniprot:A0A2R8Y7H3;uniprot:G3V3W6			
ACOT7	Protein	uniprot:O00154		ensembl:ENSG00000097021	ncbigene:11332	hgnc.symbol:ACOT7	uniprot:K7EKP8;uniprot:O00154			
ACOT8	Protein	uniprot:O14734		ensembl:ENSG00000101473	ncbigene:10005	hgnc.symbol:ACOT8	uniprot:H7C5A7;uniprot:E9PJN0;uniprot:F6VBM3;uniprot:E9PIS4;uniprot:Q9BR14;uniprot:O14734;uniprot:E9PMC4;uniprot:A0A494C0N6;uniprot:H0Y698;uniprot:E9PRD4			
ACOT9	Protein	uniprot:Q9Y305		ensembl:ENSG00000123130	ncbigene:23597	hgnc.symbol:ACOT9	uniprot:Q9Y305;uniprot:C9J7L8;uniprot:F8WDI2;uniprot:H7C5Q2			
ACOT11	Protein	uniprot:Q8WXI4		ensembl:ENSG00000162390	ncbigene:26027	hgnc.symbol:ACOT11	uniprot:Q8WXI4			
ACOT12	Protein	uniprot:Q8WYK0		ensembl:ENSG00000172497	ncbigene:134526	hgnc.symbol:ACOT12	uniprot:Q8WYK0			
ACOT13	Protein	uniprot:Q9NPJ3		ensembl:ENSG00000112304	ncbigene:55856	hgnc.symbol:ACOT13	uniprot:Q9NPJ3			
ACOT7L	Protein	uniprot:Q6ZUV0	'Could be the product of a pseudogene. The peptide used to produce antibodies against ACOT7L matches at 85% with ACOT7 and the antibodies may not be specific to ACOT7L.' [https://www.uniprot.org/uniprot/Q6ZUV0]							
ACOT15	Protein	uniprot:Q8N1Q8		ensembl:ENSG00000196407	ncbigene:284486	hgnc.symbol:THEM5	uniprot:Q8N1Q8;uniprot:H0Y6P4			
ChEH	Protein	uniprot:P34913	AKA cholesterol epoxide hydrolase (ChEH); EC: 3.3.2.11</br>'ChEH is a dimer of 7-dehydrocholesterol reductase (DHCR7) and 3β-hydroxysteroid-Δ8-Δ7-isomerase (D8D7I)'	ensembl:ENSG00000120915	ncbigene:2053	hgnc.symbol:EPHX2	uniprot:E5RFU2;uniprot:H0YAW7;uniprot:E5RFH6;uniprot:P34913;uniprot:E5RI53			
ACOT1	Protein	uniprot:Q86TX2		ensembl:ENSG00000184227	ncbigene:641371	hgnc.symbol:ACOT1	uniprot:G3V4F2;uniprot:Q86TX2;uniprot:E9KL42			
ACOT	Protein	eccode:3.1.2.2	acyl-CoA thioesterase are a group of enzymes							
ACOT2	Protein	uniprot:P49753	'originally thought to be in peroxisome [PMID:10944470)], later found to be mitochondrial [PMID:16940157]' [https://www.uniprot.org/uniprot/P49753]	ensembl:ENSG00000119673	ncbigene:10965	hgnc.symbol:ACOT2	uniprot:P49753;uniprot:F6VI00;uniprot:A0A087WT95			
ACOT4	Protein	uniprot:Q8N9L9	'Compared to mouse peroxisomal succinyl-coenzyme A thioesterase/ACOT4, the human enzyme has a broad substrate specificity overlapping the activity of three mouse acyl-coenzyme A thioesterases, providing an explanation for the unexpectedly low number of acyl-coenzyme A thioesterase genes in the human genome [PMID:16940157]' [https://www.uniprot.org/uniprot/Q8N9L9]	ensembl:ENSG00000177465	ncbigene:122970	hgnc.symbol:ACOT4	uniprot:Q8N9L9			
ACOT6	Protein	uniprot:Q3I5F7		ensembl:ENSG00000205669	ncbigene:641372	hgnc.symbol:ACOT6	uniprot:Q3I5F7;uniprot:A0A2R8Y7H3;uniprot:G3V3W6			
ACOT7	Protein	uniprot:O00154		ensembl:ENSG00000097021	ncbigene:11332	hgnc.symbol:ACOT7	uniprot:K7EKP8;uniprot:O00154			
ACOT8	Protein	uniprot:O14734		ensembl:ENSG00000101473	ncbigene:10005	hgnc.symbol:ACOT8	uniprot:H7C5A7;uniprot:E9PJN0;uniprot:F6VBM3;uniprot:E9PIS4;uniprot:Q9BR14;uniprot:O14734;uniprot:E9PMC4;uniprot:A0A494C0N6;uniprot:H0Y698;uniprot:E9PRD4			
ACOT9	Protein	uniprot:Q9Y305		ensembl:ENSG00000123130	ncbigene:23597	hgnc.symbol:ACOT9	uniprot:Q9Y305;uniprot:C9J7L8;uniprot:F8WDI2;uniprot:H7C5Q2			
ACOT11	Protein	uniprot:Q8WXI4		ensembl:ENSG00000162390	ncbigene:26027	hgnc.symbol:ACOT11	uniprot:Q8WXI4			
ACOT12	Protein	uniprot:Q8WYK0		ensembl:ENSG00000172497	ncbigene:134526	hgnc.symbol:ACOT12	uniprot:Q8WYK0			
ACOT13	Protein	uniprot:Q9NPJ3		ensembl:ENSG00000112304	ncbigene:55856	hgnc.symbol:ACOT13	uniprot:Q9NPJ3			
ACOT7L	Protein	uniprot:Q6ZUV0	'Could be the product of a pseudogene. The peptide used to produce antibodies against ACOT7L matches at 85% with ACOT7 and the antibodies may not be specific to ACOT7L.' [https://www.uniprot.org/uniprot/Q6ZUV0]							
ACOT15	Protein	uniprot:Q8N1Q8		ensembl:ENSG00000196407	ncbigene:284486	hgnc.symbol:THEM5	uniprot:Q8N1Q8;uniprot:H0Y6P4			
DHCR7	Protein	uniprot:Q9UBM7	'ChEH is a dimer of 7-dehydrocholesterol reductase (DHCR7) and 3β-hydroxysteroid-Δ8-Δ7-isomerase (D8D7I)'</br>the 3beta-hydroxysteroid delta7 reductase (DHCR7), which is the regulatory subunit. [https://en.wikipedia.org/wiki/Cholesterol-5,6-oxide_hydrolase]	ensembl:ENSG00000172893	ncbigene:1717	hgnc.symbol:DHCR7	uniprot:H0YEJ5;uniprot:E9PQ71;uniprot:E9PJ54;uniprot:B4E1K5;uniprot:H0YCS7;uniprot:H0YE57;uniprot:Q9UBM7;uniprot:E9PM00;uniprot:A0A024R5F7;uniprot:E9PRL8;uniprot:E9PLZ2;uniprot:E9PIP9			
D8D7I	Protein	uniprot:Q15125	'ChEH is a dimer of 7-dehydrocholesterol reductase (DHCR7) and 3β-hydroxysteroid-Δ8-Δ7-isomerase (D8D7I)'</br>also known as the emopamyl binding protein (EBP), which is the catalytic subunit [https://en.wikipedia.org/wiki/Cholesterol-5,6-oxide_hydrolase]	ensembl:ENSG00000147155	ncbigene:10682	hgnc.symbol:EBP	uniprot:A0A024QYX0;uniprot:C9J719;uniprot:Q15125;uniprot:C9JJ78